- Hereditary protein C deficiency with recurrent thrombosis: identification of a missense mutation (C6218T)
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Song KS, Park YS, Choi CR, Kim HK, Park Q, Kim HS
- KMID: 1064967
- J Korean Med Sci.
- 1998 Apr;13(2):186-190.
- doi: 10.3346/jkms.1998.13.2.186
Protein C is the central component of a major anti-thrombotic regulatory system and individuals with hereditary protein C deficiency (PCD) tend to have an increased risk of thromboembolism. During... -
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- Evidence that the fully assembled capsid of Leishmania RNA virus 1-4 possesses catalytically active endoribonuclease activity
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Ro YT, Kim EJ, Lee HI, Saiz M, Jr RC, Patterson
- KMID: 1380209
- Exp Mol Med.
- 2004 Apr;36(2):145-156.
In this study, Leishmania RNA virus 1-4 (LRV1-4) particles purified from host Leishmania guyanensis promastigotes were examined for capsid endoribonuclease. Temperature optimum for the endoribonulease activity was found to be... -
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- Gold compound auranofin inhibits I kappaB kinase (IKK) by modifying Cys-179 of IKK beta subunit
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Jeon KI, Byun MS, Jue DM
- KMID: 1097252
- Exp Mol Med.
- 2003 Apr;35(2):61-66.
Antirheumatic gold compounds have been shown to inhibit NF-kB activation by blocking IkB kinase (IKK) activity. To examine the possible inhibitory mechanism of gold compounds, we expressed wild type and... -
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