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The effect of cyclophosphamide on Fas-mediated apoptosis

Lee JH, Park JH, Yang MH

Fas is a cell surface protein that can mediate apoptosis and belongs to the tumor necrosis factor (TNF) receptor family. Anti-Fas antibody induces apoptotic cell death in...
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An Experimental Study on Immune Complex Induced Athritis in Rabbits: Reference to Macrophages and M-type Cells of the Synovium

Choi IJ, Seong BY, Kim TS, Lee YB

This study evaluates the pathogenesis of rheumatoid arthritis by producing immune complex induced arthritis with an intra-articular injection of BSA in immunized rabbits, and the effect of systemic administration of...
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Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S

4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily, is a major costimulatory receptor that is rapidly expressed on the surface of CD4+ and CD8+ T cells after...
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RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells

Lee HW, Park HK, Na YJ, Kim CD, Lee JH, Kim BS, Kim JB, Lee CW, Moon JO, Yoon S

Abstract In many clinical situations which cause thymic involution and thereby result in immune deficiency, T cells are the most often affected, leading to a prolonged deficiency of T cells. Since...
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