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Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver

Jeong JS, Lee JH, Kim HI, Park JI

Partial hepatectomy (PH) endorses quiescent hepatocytes to reenter the cell cycle. The regenerating liver returns to its preresection weight after 7 days, following one or two cell division and maintains...
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Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver

Hong SH, Lee GD, Chung JY, Cho KS, Park SH, Kim IH, Jeong JS

  • KMID: 755208
  • Exp Mol Med.
  • 2002 Nov;34(5):361-366.
Repetitive low dose thioacetamide (TA) treatment of hepatocytes was found to induce cells in G2 arrest. In the present study, an attempt was made to investigate alterations in expression of...
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Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer

Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY

  • KMID: 1109306
  • Exp Mol Med.
  • 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated...
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