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Effect of Amiloride to Retinal Toxicity Induced by Tissue Plasminogen Activator

Kim US, Oh HS, Kwon OW, Chung I, Lee SH, Lee JH

PURPOSE: The effects of amiloride on cellular toxicity caused by tissue plasminogen activator (tPA) in mouse primary retinal cells were investigated. METHODS: Primary retinal cell cultures were maintained using glial conditioned...
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Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase

Jang MJ, Lee MJ, Park HY, Bae YS, Min DS, Ryu SH, Kwak JY

  • KMID: 1380212
  • Exp Mol Med.
  • 2004 Apr;36(2):172-178.
Agents that elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD). We investigated whether PLD can be phosphorylated by cAMP-dependent protein kinase (PKA) and PKA-mediated phosphorylation...
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