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Rolipram, a Phosphodiesterase 4 Inhibitor, Stimulates Inducible cAMP Early Repressor Expression in Osteoblasts

Cho ES, Yu JH, Kim MS, Yim M

Phosphodiesterase (PDE) 4 inhibitors have been shown to induce the cAMP-mediated signaling pathway by inhibiting cAMP hydrolysis. This study investigated the effect of a PDE4 inhibitor on the expression of...
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Modulation of InsP3 receptor properties by phosphorylation: targeting of PKA to InsP3 receptors shapes oscillatory calcium signals in pancreatic acinar cells

Giovannucci DR, Sneyd J, Groblewski GE, Yule DI

No abstract available.
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Increased expression of Galphaq protein in the heart of streptozotocin-induced diabetic rats

Yang JM, Cho CH, Kong KA, Jang IS, Kim HW, Juhnn YS

  • KMID: 1029924
  • Exp Mol Med.
  • 1999 Dec;31(4):179-184.
Heart disease is one of the major cause of death in diabetic patients, but the thogenesis of diabetic cardio-myopathy remains unclear. In this experiment, to sess the significance...
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Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway

Jeong JS, Kim IH, Lee HJ, Choi YC

  • KMID: 755010
  • Exp Mol Med.
  • 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer...
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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins

Shah BH

  • KMID: 1029937
  • Exp Mol Med.
  • 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells...
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