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Phosphodiesterase (PDE) 4 inhibitors have been shown to induce the cAMP-mediated signaling pathway by inhibiting cAMP hydrolysis. This study investigated the effect of a PDE4 inhibitor on the expression of...
Yang JM, Cho CH, Kong KA, Jang IS, Kim HW, Juhnn YS
KMID: 1029924
Exp Mol Med.
1999 Dec;31(4):179-184.
Heart disease is one of the major cause of death in diabetic patients, but the
thogenesis of diabetic cardio-myopathy remains unclear. In this experiment, to
sess the significance...
Since there have been very few studies on nucleolar signaling, an attempt was
made to establish nucleolar signal pathways which link the cell membrane to the
nucleolus for the transfer...
Previously it has been shown that persistent activation of the stimulatory
adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha
polypeptide (80%) in a cAMP-independent manner in C6 glioma cells...