- Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase
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Jang MJ, Lee MJ, Park HY, Bae YS, Min DS, Ryu SH, Kwak JY
- KMID: 1380212
- Exp Mol Med.
- 2004 Apr;36(2):172-178.
Agents that elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD). We investigated whether PLD can be phosphorylated by cAMP-dependent protein kinase (PKA) and PKA-mediated phosphorylation... -
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- Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells
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Seo DR, Kim SY, Kim KY, Lee HG, Moon JH, Lee JS, Lee SH, Kim SU, Lee YB
- KMID: 1103584
- Exp Mol Med.
- 2008 Feb;40(1):19-26.
- doi: 10.3858/emm.2008.40.1.19
Previously we demonstrated that ATP released from LPS-activated microglia induced IL-10 expression in a process involving P2 receptors, in an autocrine fashion. Therefore, in the present study we sought to... -
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- Protein kinase A mediates microglial activation induced by plasminogen and gangliosides
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Min KJ, Yang MS, Jou I, Joe EH
- KMID: 1123767
- Exp Mol Med.
- 2004 Oct;36(5):461-467.
In the injured brain, microglia is known to be activated and produce proinflammatory mediators such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and inducible nitric oxide synthase (iNOS). We investigated... -
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