- Adaptation of cAMP signaling system in SH-SY5Y neuroblastoma cells following expression of a constitutively active stimulatory G protein alpha, Q227L Gsalpha
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Jang IS, Juhnn YS
- KMID: 755116
- Exp Mol Med.
- 2001 Mar;33(1):37-45.
Heterotrimeric GTP-binding proteins (G protein) are known to participate in the transduction of signals from ligand activated receptors to effector molecules to elicit cellular responses. Sustained activation of cAMP-G protein... -
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- Downstream molecular events in the altered profiles of lysophosphatidic acid-induced cAMP in senescent human diploid fibroblasts
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Jang IS, Rhim JH, Park SC, Yeo EJ
- KMID: 1111406
- Exp Mol Med.
- 2006 Apr;38(2):134-143.
Lysophosphatidic acid (LPA) is a phospholipid growth factor that acts through G-protein-coupled receptors. Previously, we demonstrated an altered profile of LPA-dependent cAMP content during the aging process of human diploid... -
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- Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma
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Moon HG, Kim YS, Choi JP, Choi DS, Yoon CM, Jeon SG, Gho YS, Kim YK
- KMID: 946669
- Exp Mol Med.
- 2010 Jan;42(1):47-60.
- doi: 10.3858/emm.2010.42.1.005
Theophylline is commonly used to treat severe asthma and chronic obstructive pulmonary disease (COPD) characterized by non-eosinophilic inflammation. Acetyl salicylic acid (ASA) is one of the most widely used medications... -
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- Human SNF2L Gene Is Regulated Constitutively and Inducibly in Neural Cells via a cAMP-Response Element
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Xia Y, Wang L, Ma C, Gong Y, Zhao Y
- KMID: 1727896
- Yonsei Med J.
- 2013 May;54(3):772-777.
- doi: 10.3349/ymj.2013.54.3.772
PURPOSE: SNF2L belongs to Imitation Switch family and plays an essential role in neural tissues and gonads. In our previous studies, we have demonstrated that the basal transcription of human... -
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- Multi-facet expressions of adenylate cyclase isoforms in B16-F10 melanoma cells differentiated by forskolin treatment
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Cho DH, Bae CD, Juhnn YS
- KMID: 755106
- Exp Mol Med.
- 2000 Dec;32(4):235-242.
The terminal differentiation of malignant melanoma cells is known to be induced by activating cAMP signaling pathway with alpha-MSH or cAMP analogues. However, sustained activation of cAMP signaling... -
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