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Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans

Son YE, Jung WH, Oh SH, Kwak JH, Cardenas M, Park HS

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized...
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Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea

Park SH, Choi SC, Lee KW, Kim MN, Hwang SM

Multilocus sequence typing analysis was applied to determine the genotypes of 147 (137 clinical and 10 environmental) Cryptococcus neoformans and three clinical Cryptococcus gattii isolates from 1993 to 2014 in...
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Cryptococcus neoformans Cellulitis with Cryptococcemia in a Patient on Maintenance Hemodialysis

Jeong IW, Kim JE, Kim SH, Kim JH, Hong YA, Ko GJ, Kwon YJ

Cryptococcus neoformans is a fungus that causes opportunistic infections in immunocompromised hosts. Skin lesions are found in 10-20% of systemic cryptococcal infections, usually secondary to cryptococcemia, while primary cutaneous cryptococcosis...
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Mitochondrial Protein Nfu1 Influences Homeostasis of Essential Metals in the Human Fungal Pathogen Cryptococcus neoformans

Kim J, Park M, Do E, Jung WH

Mitochondrial protein Nfu1 plays an important role in the assembly of mitochondrial Fe-S clusters and intracellular iron homeostasis in the model yeast Saccharomyces cerevisiae. In this study, we identified the...
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A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway

Lee KT, Lee JW, Lee D, Jung WH, Bahn YS

  • KMID: 2312738
  • Mycobiology.
  • 2014 Jun;42(2):152-157.
The iron uptake and utilization pathways play a critical role in allowing human pathogens, including Cryptococcus neoformans, the causative agent of fatal meningoencephalitis, to survive within the mammalian body by...
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Molecular Epidemiology of Clinical Cryptococcus neoformans Isolates in Seoul, Korea

Park SH, Kim M, Joo SI, Hwang SM

  • KMID: 2312726
  • Mycobiology.
  • 2014 Mar;42(1):73-78.
Cryptococcal infection is primarily caused by two species, Cryptococcus neoformans and C. gattii. Between the two species, C. neoformans var. grubii is the major causative agent of cryptococcosis in Asia....
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A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans

Lee KT, Kwon H, Lee D, Bahn YS

  • KMID: 2312723
  • Mycobiology.
  • 2014 Mar;42(1):52-58.
A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been identified as one of the gromwell plant extract-responsive genes in Cryptococcus neoformans. Ysa1 is known to control intracellular concentrations...
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Isolation and Characterization of Cryptococcus neoformans from Environmental Sources in Busan

Oh KS, Hwang SM

  • KMID: 2312467
  • Mycobiology.
  • 2005 Dec;33(4):188-193.
Twenty nine samples of pigeon droppings (n = 12) and soil contaminated with avian excreta (n = 19), collected from different sites in Busan, were examined for isolation and characterization...
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Fungistatic Activity of Kojic Acid Against Human Pathogenic Fungi and Inhibition of Melanin-production in Cryptococcus neoformans

Chee HY, Lee EH

  • KMID: 2312421
  • Mycobiology.
  • 2003 Dec;31(4):248-250.
Kojic acid was investigated for its antifungal activity against the human pathogenic fungi including Candida albicans, Cryptococcus neoformans and Trichophyton rubrum. For C. albicans, C. neoformans and T. rubrum, the...
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Isolation of Cryptococcus neoformans var. grubii (serotype A) from Pigeon Droppings in Korea

Chee HY, Kim YK

Three hundred and sixty five samples of avian droppings, collected from parks and zoo, were investigated for the occurrence of Cryptococcus neoformans in Korea. Thirteen samples were positive for C....
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In Vitro Antifungal Activities of Amphotericin B, Fluconazole, Itraconazole, Terbinafine, Caspofungin, Voriconazole, and Posaconazole against 30 Clinical Isolates of Cryptococcus neoformans var. neoformancs

Lee YK, Fothergill AW

  • KMID: 2312406
  • Mycobiology.
  • 2003 Jun;31(2):95-98.
Aantifungal agents were tested against 30 clinical isolates of Cryptococcus neoformans var. neoformans using the NCCLS method (M27-A2). Posaconazole, itraconazole and amphotericin B had lower MIC than the remaining four...
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In vitro Evaluation of the Antifungal Activity of Propolis Extract on Cryptococcus neoformans and Candida albicans

Chee HY

  • KMID: 2312376
  • Mycobiology.
  • 2002 Jun;30(2):93-95.
The antifungal activities of propolis on Cryptococcus neoformans and Candida albicans were evaluated. In microbroth culture assay, the MIC (minimum inhibitory concentration) of propolis for C. neoformans and C. albicans...
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In Vitro Activities of LY303366 against Clinical Isolates of Candida spp., Cryptococcus neoformans and Aspergillus spp.

Lee K, Yong D, Shin HB, Kim YA, Chong Y

  • KMID: 2248594
  • Korean J Infect Dis.
  • 2000 Aug;32(4):274-279.
BACKGROUND: Fungal infection became more prevalent with the increase of compromised patients, requiring less toxic potent antifungal agents. LY303366, a new semisynthetic antifungal agent of echinocandin class, was reported to...
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Differentiation of Varieties and Susceptibility Testing for Two Strains of Cryptococcus neoformans

Kim JW, Jang S, Kang JO, Choi TY

  • KMID: 2300530
  • Korean J Clin Pathol.
  • 1998 Dec;18(4):550-553.
Typing of cryptococcal varieties and antifungal susceptibility testing were performed on two strains which were isolated from a nonimmunosuppressed host with cryptococcal meningitis and another from a patient with systemic...
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Enhancing effect of IL-2, IFN-gamma and poly(A). poly(U) on growth inhibition of murine lymphocytes against cryptococcus neoformans

Park YM, Ha TY, Park BS

  • KMID: 1687888
  • J Korean Soc Microbiol.
  • 1991 Feb;26(1):105-116.
No abstract available.
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A Ultramicroscopic Study Cryptococcus Neoformans Derived from Pigeon Drops

Suh JH, Suh SB

  • KMID: 2039167
  • Korean J Dermatol.
  • 1977 Sep;15(3):297-303.
The morphologic differences hetween a mucoid and pasty type of Cryptococcus neoformans derived from pigeon drops were investigated using an eIectron microscope. The following results were obtained: No essential differences...
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