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Outcomes of Fertility Preservation for Female Cancer Patients in a Single Tertiary Center

Kim JH, Alzahrani HS, Lee SR, Kim SH, Chae HD

Purpose: To report our experience of fertility preservation (FP) in female cancer patients. Materials and Methods: We retrospectively analyzed the medical records of female who underwent elective oocyte or embryo cryopreservation...
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Human sperm parameter improvement associated with Ceratonia siliqua extract as a cryopreservation supplement after vitrification

Farazmand T, Mansouri F, Koohestanidehaghi Y, Shahandeh E

Objective: Given the destructive effects of oxidative stress on sperm structure, this study was conducted to investigate the antioxidant effects of different concentrations of Ceratonia siliqua plant extract on human...
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Long-Term Fertility Function Sequelae in Young Male Cancer Survivors

Yumura Y, Takeshima T, Komeya M, Karibe J, Kuroda S, Saito T

With advances in cancer treatment, such as cytotoxic chemotherapy and radiotherapy, grave new sequelae of treatment have emerged for young cancer survivors. One sequela that cannot be overlooked is male...
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Sperm DNA fragmentation in consecutive ejaculates from patients with cancer for sperm cryopreservation

Kim SK, Paik H, Lee JR, Jee BC

Objective: This prospective consecutive study investigated the variation in sperm DNA fragmentation (SDF) in multiple semen samples from patients with cancer. Methods: Eighty-one patients with various cancers underwent multiple semen collections...
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A study of delayed tooth autotransplantation after long-term cryopreservation with platelet-rich plasma in dogs

Lee SH, Ham SJ, Choi JI, Kim YJ, Moon JW

Tooth autotransplantation refers to tooth transplantation from the donor to the recipient site of the same individual. Occasionally, there are situations where autotransplantation cannot be carried out immediately at clinic....
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Planned oocyte cryopreservation for fertility preservation

Lee D, Kim YJ

Background: Oocyte cryopreservation opens up opportunities for women to preserve fertility when it is necessary to postpone pregnancy. After the advent of vitrification, the results of oocyte cryopreservation were significantly...
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Ovarian tissue cryopreservation and transplantation for fertility preservation

Hong YH, Lee JR

Background: As the number of cancer survivors has increased with advancements in cancer treatment, fertility preservation has become a treatment goal. Ovarian tissue cryopreservation (OTC) and transplantation (OTT) has made...
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Cryopreservation of oocytes and embryos for fertility preservation

Lee JH, Choi YS

Background: In recent years, the demand for fertility preservation for both oncologic and nononcologic reasons, as well as for personal reasons, has increased dramatically. Current Concepts: Currently, embryo and oocyte cryopreservation...
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Fertility preservation for patients with cancer

Lee S, Kim T

Background: The survival rate of cancer patients is increasing owing to the early diagnosis and treatment methods. Radiotherapy and chemotherapy may cause serious complications, such as ovarian failure and infertility....
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History of fertility preservation

Kim HY, Kim SW

Background: Fertility preservation refers to a procedure performed to maintain the ability to become pregnant before receiving treatment with a risk of fertility loss, such as chemo- or radiation therapy....
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Fertility preservation in women: where we are now and the path we need to take

Lee J, Lee TH

Background: In its short history, reproductive medicine has achieved many fertility-related milestones, including: the arrival of in vitro fertilization in the late 1970s, the development of intracytoplasmic sperm injection in...
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Effect of aqueous Nigella sativa extract on the functional parameters of post-thaw human spermatozoa during vitrification

Nasiri Z, Ghorbani F, Seify M, Sharbati A

Objective: Sperm vitrification leads to the production of reactive oxygen species (ROS) that can damage the functional parameters of sperm. The present study aimed to investigate the antioxidant effect of...
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Development of Cryopreserved Red Blood Cell Panels as Biological Reference Standards for Performance Evaluation of ABO and D Blood Grouping Reagents

Cho YK, Kim S, Lim J, Ko DH, Choi SJ, Kim HO

Background: Accurate blood typing is essential for blood transfusions, and requires the constant evaluation and maintenance of ABO and D blood grouping reagents. In the present study, we developed cryopreserved...
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Supplementation of cryoprotective extender with resveratrol decreases apoptosis index and reactive oxygen species levels in post-thaw dog sperm

Bang S, Tanga BM, Qamar AY, Fang X, Seong G, Nabeel AHT, Yu I, Cho J

Resveratrol (RSV, 3,5,4′-trihydroxytrans-stilbene) protects sperm from cryo-induced damage in various animal and human species. In this study, we aimed to assess the effect of dog sperm cryoprotective extender containing RSV...
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Influence of hydrogel encapsulation during cryopreservation of ovarian tissues and impact of post-thawing in vitro culture systems in a research animal model

Thuwanut P, Comizzoli P, Pimpin A, Srituravanich W, Sereepapong W, Pruksananonda K, Taweepolcharoen C, Tuntiviriyapun P, Suebthawinkul C, Sirayapiwat P

Objective: Using domestic cats as a biomedical research model for fertility preservation, the present study aimed to characterize the influences of ovarian tissue encapsulation in biodegradable hydrogel matrix (fibrinogen/thrombin) on...
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The clinical outcomes of fresh versus frozen embryos transfer in women ≥40 years with poor ovarian response

Liu C, Li Y, Jiang H, Liu Y, Song X

Objective To compare the clinical outcomes of fresh embryo transfers (ETs) and frozen-thawed embryo transfers (FETs) after a freeze-all cycle in women ≥40 years old with poor ovarian response (POR). Methods...
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Effect of a dual trigger on oocyte maturation in young women with decreased ovarian reserve for the purpose of elective oocyte cryopreservation

Kim SJ, Kim TH, Park JK, Eum JH, Lee WS, Lyu SW

Objective: The aim of this study was to determine whether co-administration of a gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG) for final oocyte maturation improved mature oocyte cryopreservation...
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Psychosocial Risks Assessment in Cryopreservation Laboratories

Fernandes A, Figueiredo M, Ribeiro J, Neves J, Vicente H

Background Psychosocial risks are increasingly a type of risk analyzed in organizations beyond chemical, physical, and biological risks. To this type of risk, a greater attention has been given following the...
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Cryopreservation of mouse resources

Takeo T, Nakao S, Nakagawa Y, Sztein JM, Nakagata N

The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived...
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Effects of Cryopreservation and Thawing on Single-Cell Transcriptomes of Human T Cells

Lee JS, Yi K, Ju YS, Shin EC

Cryopreservation and thawing of PBMCs are inevitable processes in expanding the scale of experiments in human immunology. Here, we carried out a fundamental study to investigate the detailed effects of...
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