- Accelerating next generation sequencing data analysis: an evaluation of optimized best practices for Genome Analysis Toolkit algorithms
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Franke KR, Crowgey EL
- KMID: 2501330
- Genomics Inform.
- 2020 Mar;18(1):e10.
- doi: 10.5808/GI.2020.18.1.e10
Advancements in next generation sequencing (NGS) technologies have significantly increased the translational use of genomics data in the medical field as well as the demand for computational infrastructure capable processing... -
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- Strong concordance between RNA structural and single nucleotide variants identified via next generation sequencing techniques in primary pediatric leukemia and patient-derived xenograft samples
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Barwe SP, Gopalakrisnapillai A, Mahajan N, Druley TE, Kolb EA, Crowgey EL
- KMID: 2501326
- Genomics Inform.
- 2020 Mar;18(1):e6.
- doi: 10.5808/GI.2020.18.1.e6
Acute leukemia represents the most common pediatric malignancy comprising diverse subtypes with varying prognosis and treatment outcomes. New and targeted treatment options are warranted for this disease. Patient-derived xenograft (PDX)... -
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