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Multiplexed Representation of Itch and Pain and Their Interaction in the Primary Somatosensory Cortex

Woo S, Kim YR, Bak MS, Chung G, Kim SJ, Kim SK

  • KMID: 2535063
  • Exp Neurobiol.
  • 2022 Oct;31(5):324-331.
  • doi: 10.5607/en22029
Itch and pain are distinct sensations that share anatomically similar pathways: from the periphery to the brain. Over the last decades, several itchspecific neural pathways and molecular markers have been...
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Synaptic Remodeling of the Auditory Cortex Following Bilateral Blindness: Evidence of Cross-modal Plasticity

Han JJ, Noh TS, Suh MW, Kim SH, Kim DH, Kim SJ, Oh SH

  • KMID: 2535061
  • Exp Neurobiol.
  • 2022 Oct;31(5):299-306.
  • doi: 10.5607/en22020
We aimed to evaluate structural dynamic changes of neurons in the auditory cortex after visual deprivation. We longitudinally tracked dendritic spines for 3 weeks after visual deprivation in vivo using...
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Medial prefrontal cortex nitric oxide modulates neuropathic pain behavior through mu opioid receptors in rats

Raisian D, Erfanparast A, Tamaddonfard E, Soltanalinejad-Taghiabad F

Background: The neocortex, including the medial prefrontal cortex (mPFC), contains many neurons expressing nitric oxide synthase (NOS). In addition, increasing evidence shows that the nitric oxide (NO) and opioid systems...
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Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α

Park J, Cheon JH

The incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties. The...
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The Three Musketeers in the Medial Prefrontal Cortex: Subregion-specific Structural and Functional Plasticity Underlying Fear Memory Stages

Sung Y, Kaang BK

  • KMID: 2532833
  • Exp Neurobiol.
  • 2022 Aug;31(4):221-231.
  • doi: 10.5607/en22012
Fear memory recruits various brain regions with long-lasting brain-wide subcellular events. The medial prefrontal cortex processes the emotional and cognitive functions required for adequately handling fear memory. Several studies have...
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A Comparison of Phenolic Components in Cinnamon Medicines

Kim CW, Ko JH, Kim DH, Jin D, Ko SK

As a result of comparing the phenolic components of cinnamon medicines, the total phenolic component content of Cinnamomi Cortex in China was about 2.65 times higher than that of Cinnamomi...
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The Indirect Effect of Prefrontal Gray Matter Volume on Suicide Attempts among Individuals with Major Depressive Disorder

Kang J, Kim A, Kang Y, Han KM, Ham BJ

Trait impulsivity is a known risk factor for suicidality, and the prefrontal cortex plays a key role in impulsivity and its regulation. However, the relationship between trait impulsivity, neural basis,...
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Altered synaptic connections and inhibitory network of the primary somatosensory cortex in chronic pain

Kim YR, Kim SJ

Chronic pain is induced by tissue or nerve damage and is accompanied by pain hypersensitivity (i.e., allodynia and hyperalgesia). Previous studies using in vivo two-photon microscopy have shown functional and...
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Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up

Annaniemi JA, Pere J, Giordano S

Background: Given the complications involved in corticosteroid (CS) injections, subacromial platelet-rich plasma (PRP) injections may provide a valid alternative to CS in the treatment of rotator cuff (RC) tendinopathy. Methods:...
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Adrenal Morphology as an Indicator of Long-Term Disease Control in Adults with Classic 21-Hydroxylase Deficiency

Kim TM, Kim JH, Jang HN, Choi MH, Cho JY, Kim SY

Background: Monitoring adults with classical 21-hydroxylase deficiency (21OHD) is challenging due to variation in clinical and laboratory settings. Moreover, guidelines for adrenal imaging in 21OHD are not yet available. We...
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Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing

Boo SH, Jeong SW

Background and Objectives: To examine the maturational status of the auditory cortex in adults with cochlear implants (CIs) using the latencies of the P1, N1, and P2 components of cortical...
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Effects of Cognitive-Physical DualTask Training on Executive Function and Activity in the Prefrontal Cortex of Older Adults with Mild Cognitive Impairment

Park JH

Effects of cognitive-physical dual-task training on prefrontal cortex (PFC)-dependent function remain unclear. This study investigated the effects of dual-task training on executive function and activity in the PFC of older...
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Pure Cortical Ependymoma With RELA-Fusion Positive in a Young Adult

Lee SW, Lee JH, Lee MS, Suh SJ, Lee YS, Kim JW

A 25-year-old female presented with a generalized tonic-clonic seizure. She had no previous history of seizures. A brain magnetic resonance imaging scan revealed a solitary enhancing mass in the right...
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Alterations in the Occipital Cortex of Drug-Naïve Adults With Major Depressive Disorder: A Surface-Based Analysis of Surface Area and Cortical Thickness

Lee JS, Kang W, Kang Y, Kim A, Han KM, Tae WS, Ham BJ

Objective Advances in surface-based morphometric methods have allowed researchers to separate cortical volume into cortical thickness (CTh) and surface area (SA). Although CTh alterations in major depressive disorder (MDD) have...
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Association of Prefrontal Cortex Thinning with High Impulsivity in Healthy Adults

Lim JE, Kim S, Seo S, Kang W, Kim A, Kang Y, Choi KW, Tae WS, Ham BJ, Han KM

Objective Studies have been conducted to identify brain structural alterations related to high impulsivity in psychiatric populations. However, research on healthy subjects is relatively less extensive. Therefore, we aimed to...
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Transcranial direct current stimulation for spinal cord injuryassociated neuropathic pain

Li C, Jirachaipitak S, Wrigley P, Xu H, Euasobhon P

Several types of pain occur following spinal cord injury (SCI); however, neuropathic pain (NP) is one of the most intractable. Invasive and non-invasive brain stimulation techniques have been studied in...
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Verbal Auditory Agnosia Developed after Unilateral Temporal Lobe Infarction

Jeon JB, Jeon MC, Lee DH

Stroke results in sudden loss of function related to its damaged portion. When this occurs in temporal lobe, the function of hearing and listening may be affected, although receptive language...
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Role of Medial Prefrontal Cortical Neurons and Oxytocin Modulation in the Establishment of Social Buffering

Jung T, Jang M, Noh J

Fear-related behaviors are rigidly controlled by the medial prefrontal cortex (mPFC). The mPFC is activated by the prosocial hormone oxytocin, which plays an important role in social buffering. We used...
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Isolated Complete Tongue Paralysis as a Manifestation of Focal Cortical Infarction

Kang YR, Choi HS, Park HJ, Kim S, Kang KH, Park JW, Park MS, Cho KH

Although isolated contralateral tongue deviation following unilateral cortical infarction was occasionally reported, the unilateral lesion usually produces no significant deficit of tongue motility considering bilateral supranuclear innervation of the hypoglossal...
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Multiplexed Processing of Vibrotactile Information in the Mouse Primary Somatosensory Cortex

Kim YR, Kim CE, Yoon H, Kim SK, Kim SJ

  • KMID: 2510505
  • Exp Neurobiol.
  • 2020 Dec;29(6):425-432.
  • doi: 10.5607/en20041
The primary somatosensory (S1) cortex plays a key role in distinguishing different sensory stimuli. Vibrotactile touch information is conveyed from the periphery to the S1 cortex through three major classes...
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