- Impact of the COVID-19 Pandemic on Public Cord Blood Banks in Korea
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Goh R, Kim JA, Park S, Shim J, Kwak MS, Kim KH
- KMID: 2532795
- Korean J Blood Transfus.
- 2022 Aug;33(2):114-117.
- doi: 10.17945/kjbt.2022.33.2.1 1 4
The COVID-19 pandemic has had a major impact worldwide, making it difficult to transplant unrelated hematopoietic stem cells. On the other hand, cord blood transplantations in Korea increased during the... -
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- Immunomodulatory Effect of Epidermal Growth Factor Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Atopic Dermatitis
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Jung N, Kong T, Yu Y, Park H, Lee E, Yoo S, Baek S, Lee S, Kang KS
- KMID: 2532405
- Int J Stem Cells.
- 2022 Aug;15(3):311-323.
- doi: 10.15283/ijsc21173
Background and Objectives: Human mesenchymal stem cells (MSCs) are emerging as a treatment for atopic dermatitis (AD), a chronic inflammatory skin disorder that affects a large number of people across... -
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- Combined Mesenchymal Stem Cells and Cartilage Acellular Matrix Injection Therapy for Osteoarthritis in Goats
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Kim M, Ahn J, Lee J, Song S, Lee S, Lee S, Kang KS
- KMID: 2525416
- Tissue Eng Regen Med.
- 2022 Feb;19(1):177-187.
- doi: 10.1007/s13770-021-00407-3
Background: Human umbilical cord blood-derived MSCs (hUCB-MSCs) have been studied in osteoarthritis (OA) and cartilage regeneration. Our previous study demonstrated that hUCB-MSCs combined with cartilage acellular matrix injection (CAM Inj.) represent... -
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- Ruxolitinib for Treating Steroid-Refractory Acute Graft-Versus-Host Disease in an Infant with Malignant Osteopetrosis Who Received Double-Unit Umbilical Cord Blood Transplantation
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Jue JH, Shim YJ, Kim SA, Jung HR
- KMID: 2523697
- Keimyung Med J.
- 2021 Dec;40(2):119-124.
- doi: 10.46308/kmj.2021.00115
A 3-month-old male infant was transferred to our hospital due to bicytopenia. His bone marrow biopsy showed irregular bony trabeculae with cartilaginous core, which was consistent with osteopetrosis. In the... -
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- Distinct Repopulation Activity in Hu-Mice between CBand LPB-CD34＋ Cells by Enrichment of Transcription Factors
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Han AR, Lee JE, Lee MJ, Ko SY, Shin HS, Lee JY, Lee DR
- KMID: 2515996
- Int J Stem Cells.
- 2021 May;14(2):203-211.
- doi: 10.15283/ijsc21015
Background and Objectives: Human CD34＋hematopoietic stem cells can reconstitute the human hematopoietic system when transplanted into immunocompromised mice after irradiation. Human leukapheresis peripheral blood (LPB)-and cord blood (CB)-derived CD34＋ cells... -
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- Conditioning with 10 Gy Total Body Irradiation, Cyclophosphamide, and Fludarabine without ATG Is Associated with Improved Outcome of Cord Blood Transplantation in Children with Acute Leukemia
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Cho HW, Ju HY, Hyun JK, Lee Jw, Sung KW, Koo HH, Lim DH, Yoo KH
- KMID: 2515863
- J Korean Med Sci.
- 2021 May;36(19):e128.
- doi: 10.3346/jkms.2021.36.e128
Background: The optimal conditioning regimen in cord blood transplantation (CBT) needs to be determined. This study aimed to identify the impact of conditioning regimen on the outcome of CBT in... -
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- Strategies to enhance graft performance in cord blood transplantation
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Yoo KH
- KMID: 2514314
- Precis Future Med.
- 2021 Mar;5(1):1-12.
- doi: 10.23838/pfm.2020.00149
Umbilical cord blood (CB) serves as one of the alternative donor sources for hematopoietic stem cell transplantation (HSCT) in those patients lacking a matched related donor. However, the relatively high... -
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- Improving Storage Policy in Korean Public Cord Blood Banks: Comparison of Quality between Long-Term and Short-Term Storage of Cord Blood
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Lee MN, Kim KH, Kim BG, Goh RY, Kim JN
- KMID: 2505397
- Korean J Blood Transfus.
- 2020 Aug;31(2):119-130.
- doi: 10.17945/kjbt.2020.31.2.119
Background: The decreased use of cord blood units (CBU) due to improvements in haploidentical transplantation is a financial burden for public cord blood banks. Currently, there is no guidance regarding... -
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- Identification of MicroRNA Related to the CD34+ Cell Fraction of Cord Blood Stem Cells
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Lee JH, Song EY, Kim N, Roh EY, Park HW, Yoon JH, Shin S
- KMID: 2457170
- Korean J Blood Transfus.
- 2019 Aug;30(2):113-123.
- doi: 10.17945/kjbt.2019.30.2.113
BACKGROUND: Cord blood (CB) is a reliable source of hematopoietic stem cells, and its utilization in stem cell transplantation is increasing continuously. The CD34+ cell count is arguably one of... -
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- Mesenchymal Stem Cells from the Wharton's Jelly of the Human Umbilical Cord: Biological Properties and Therapeutic Potential
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Marino L, Castaldi M, Rosamilio , Ragni E, Vitolo R, Fulgione C, Castaldi S, Serio B, Bianco R, Guida M, Selleri C
- KMID: 2465893
- Int J Stem Cells.
- 2019 Jul;12(2):218-226.
- doi: 10.15283/ijsc18034
Wharton's jelly mesenchymal stem cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical... -
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- Successful engraftment after infusion of multiple low doses of CD34+ cells from a poorly matched sibling donor in a patient with severe aplastic anemia
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Kum CD, Lee MJ, Park JE
- KMID: 2449328
- Yeungnam Univ J Med.
- 2019 May;36(2):148-151.
- doi: 10.12701/yujm.2019.00038
The dose of CD34+ cells is known to influence the outcome of allogeneic peripheral blood stem cell (PBSC) and/or T-cell-depleted transplantation. A previous study proposed that 2×10ⶠCD34+ cells/kg is... -
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- Leukocyte Telomere Length Reflects Prenatal Stress Exposure, But Does Not Predict Atopic Dermatitis Development at 1 Year
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Suh DI, Kang MJ, Park YM, Lee JK, Lee SY, Sheen YH, Kim KW, Ahn K, Won HS, Lee MY, Choi SJ, Kwon JY, Park HJ, Jun JK, Hong SJ, Koh YY
- KMID: 2442047
- Allergy Asthma Immunol Res.
- 2019 May;11(3):357-366.
- doi: 10.4168/aair.2019.11.3.357
PURPOSE: Prenatal maternal stress affects offspring's atopic dermatitis (AD) development, which is thought to be mediated by the oxidative stress. We aimed to evaluate the difference in leukocyte telomere length... -
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- Effect of Maternal Depression on Brain-derived Neurotrophic Factor Levels in Fetal Cord Blood
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Sonmez EO, Uguz F, Sahingoz M, Sonmez G, Kaya N, Camkurt MA, Gokmen Z, Basaran M, Gezginc K, Erdem SS, Dulger HH, Tasyurek E
- KMID: 2456734
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):308-313.
- doi: 10.9758/cpn.2019.17.2.308
OBJECTIVE: We aimed to assess the association between cord blood brain-derived neurotrophic factor (BDNF) concentration and maternal depression during pregnancy. METHODS: A total of 48 pregnant women, admitted for elective caesarean... -
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- Haptoglobin Concentration in the Cord Blood of Uninfected Korean Newborns
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Choi SJ, Lee B, Ahn K, Uh Y
- KMID: 2430219
- Perinatology.
- 2018 Dec;29(4):165-169.
- doi: 10.14734/PN.2018.29.4.165
OBJECTIVE: Highly sensitive haptoglobin measurement should be used in neonates because the haptoglobin concentration in neonates is lower than that of adults. The aim of this study was to establish... -
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- MiR-9 Controls Chemotactic Activity of Cord Blood CD34⺠Cells by Repressing CXCR4 Expression
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Ha TW, Kang HS, Kim TH, Kwon JH, Kim HK, Ryu A, Jeon H, Han J, Broxmeyer , Hwang Y, Lee YK, Lee MR
- KMID: 2429551
- Int J Stem Cells.
- 2018 Nov;11(2):187-195.
- doi: 10.15283/ijsc18057
Improved approaches for promoting umbilical cord blood (CB) hematopoietic stem cell (HSC) homing are clinically important to enhance engraftment of CB-HSCs. Clinical transplantation of CB-HSCs is used to treat a... -
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- Safety of Autologous Umbilical Cord Blood Therapy for Acquired Sensorineural Hearing Loss in Children
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Baumgartner LS, Moore E, Shook D, Messina S, Day MC, Green J, Nandy R, Seidman M, Baumgartner JE
- KMID: 2428989
- J Audiol Otol.
- 2018 Oct;22(4):209-222.
- doi: 10.7874/jao.2018.00115
BACKGROUND AND OBJECTIVES: Sensorineural hearing loss (SNHL) in children is associated with neurocognitive morbidity. The cause of SNHL is a loss of hair cells in the organ of Corti. There... -
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- Storage and use of cord blood
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Lee YH
- KMID: 2420367
- J Korean Med Assoc.
- 2018 Sep;61(9):557-565.
- doi: 10.5124/jkma.2018.61.9.557
Cord blood (CB) has been used as an important source for hematopoietic stem cell transplantation and has been stored in public CB banks (CBBs) worldwide since the mid-1990s. Recently, the... -
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- Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia
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Zhang X, Li Z, Geng W, Song B, Wan C
- KMID: 2412655
- Yonsei Med J.
- 2018 Jul;59(5):643-651.
- doi: 10.3349/ymj.2018.59.5.643
PURPOSE: To investigate the efficacy and safety of umbilical cord blood (UCB) infusion (UCBI) plus immunosuppressive therapy (IST) treatment in comparison to IST treatment, as well as predictive factors for... -
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- Terminally Differentiating Eosinophils Express Neutrophil Primary Granule Proteins as well as Eosinophil-specific Granule Proteins in a Temporal Manner
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Kim K, Hwang SM, Kim SM, Park SW, Jung Y, Chung IY
- KMID: 2400627
- Immune Netw.
- 2017 Dec;17(6):410-423.
- doi: 10.4110/in.2017.17.6.410
Neutrophils and eosinophils, 2 prominent granulocytes, are commonly derived from myelocytic progenitors through successive stages in the bone marrow. Our previous genome-wide transcriptomic data unexpectedly showed that genes encoding a... -
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- Direct Conversion of Human Umbilical Cord Blood into Induced Neural Stem Cells with SOX2 and HMGA2
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Kim JJ, Shin JH, Yu KR, Lee BC, Kang I, Lee JY, Kim DH, Seo Y, Kim HS, Choi SW, Kang KS
- KMID: 2400876
- Int J Stem Cells.
- 2017 Nov;10(2):227-234.
- doi: 10.15283/ijsc17025
Recent advances have shown the direct reprogramming of mouse and human fibroblasts into induced neural stem cells (iNSCs) without passing through an intermediate pluripotent state. Thus, direct reprogramming strategy possibly... -
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