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Risk factors for type-specific persistence of high-risk human papillomavirus and residual/recurrent cervical intraepithelial neoplasia after surgical treatment

Ouh YT, Cho HW, Kim SM, Min KJ, Lee SH, Song JY, Lee JK, Lee NW, Hong JH

Objective This study aimed to investigate the clinicopathologic risk factors for type-specific persistence of high-risk human papillomavirus (hrHPV) and residual/recurrent cervical intraepithelial neoplasia (CIN) after surgical treatment. Methods Patients with CIN-2/3...
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Age-specific predictors of cervical dysplasia recurrence after primary conization: analysis of 3,212 women

Bogani G, Pinelli C, Chiappa V, Martinelli F, Lopez S, Ditto A, Raspagliesi F

Objective: This study aimed to identify predictors of recurrence/persistence of cervical intraepithelial neoplasia grade 2+ (CIN2+) lesion (r-CIN2+) after primary conization. Methods: Retrospective analysis involving all consecutive women having conization for...
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Pathologic discrepancies between colposcopy-directed biopsy and loop electrosurgical excision procedure of the uterine cervix in women with cytologic high-grade squamous intraepithelial lesions

Kim SI, Kim SJ, Suh DH, Kim K, No JH, Kim YB

OBJECTIVE: To investigate pathologic discrepancies between colposcopy-directed biopsy (CDB) of the cervix and loop electrosurgical excision procedure (LEEP) in women with cytologic high-grade squamous intraepithelial lesions (HSILs). METHODS: We retrospectively identified...
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Artificial Neural Network Analysis of Spontaneous Preterm Labor and Birth and Its Major Determinants

Lee KS, Ahn KH

BACKGROUND: Little research based on the artificial neural network (ANN) is done on preterm birth (spontaneous preterm labor and birth) and its major determinants. This study uses an ANN for...
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Hemoperitoneum: a complication of loop electrosurgical excision procedure

Cho A, Park S, Park S, Kang HS, Shim SS, Park CM, Kim SY

Loop electrosurgical excision procedure (LEEP) is commonly performed for the management of cervical intraepithelial neoplasia. Although LEEP is considered to be a relatively simple procedure, several unexpected complications have been...
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Clinical factors that affect diagnostic discrepancy between colposcopically directed biopsies and loop electrosurgical excision procedure conization of the uterine cervix

Jung Y, Lee AR, Lee SJ, Lee YS, Park DC, Park EK

OBJECTIVE: This study aimed to determine the factors affecting pathologic discrepancy and final diagnosis between colposcopic biopsy and pathology by loop electrosurgical excision procedure (LEEP). METHODS: Between 2004 and 2016, 1,200...
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The use of conization to identify and treat severe lesions among prediagnosed CIN1 and 2 patients in Japan

Mikami M, Ikeda M, Sato H, Iwase H, Enomoto T, Kobayashi , Katabuchi

OBJECTIVE: To evaluate the clinical efficiency of identifying patients with suspicious severe lesions by conization among prediagnosed cervical intraepithelial neoplasia (CIN) 1 and 2 patients in Japan. METHODS: The data in...
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Identification of appropriate cone length to avoid positive cone margin in high grade cervical intraepithelial neoplasia

Kawano K, Tsuda N, Nishio S, Yonemoto K, Tasaki K, Tasaki R, Ushijima K

OBJECTIVE: To identify key factors for predicting positive cone margin and appropriate cone length. METHODS: We retrospectively reviewed the margin status of patients who received conization with high grade cervical intraepithelial...
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A human papillomavirus (HPV)-16 or HPV-18 genotype is a reliable predictor of residual disease in a subsequent hysterectomy following a loop electrosurgical excision procedure for cervical intraepithelial neoplasia 3

Kang WD, Ju UC, Kim SM

OBJECTIVE: This study was conducted using the human papillomavirus (HPV) DNA chip test (HDC), in order to determine whether the HPV genotype is a predictor of residual disease in a...
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Pseudoaneurysm of uterine artery causing intra-abdominal and vaginal bleeding after cervical conization

Moon G, Jeon S, Nam KH, Choi S, Sunwoo J, Ryu A

Uterine arterial pseudoaneurysm is a very rare condition usually associated with postpartum hemorrhage. It almost never occurs after cervical conization; however, since ruptured pseudoaneurysm could be life threatening, we should...
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Clinical Implication of p16, Ki-67, and Proliferating Cell Nuclear Antigen Expression in Cervical Neoplasia: Improvement of Diagnostic Accuracy for High-grade Squamous Intraepithelial Lesion and Prediction of Resection Margin Involvement on Conization Specimen

Kim TH, Han JH, Shin E, Noh JH, Kim HS, Song YS

BACKGROUND: Cervical intraepithelial neoplasia (CIN) grading is subjective and affected by substantial rates of discordance among pathologists. Although the use of p16INK4a (p16) staining has been proven to improve diagnostic...
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Analysis of treatment modalities and prognosis on microinvasive cervical cancer: a 10-year cohort study in China

Qian Q, Yang J, Cao D, You Y, Chen J, Shen K

OBJECTIVE: To explore appropriate treatment modality of microinvasive cervical cancer (MIC) and to analyze prognosis and risk factors of recurrence. METHODS: A cohort of 324 Chinese patients with MIC diagnosed and...
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Tumor volume and lymphovascular space invasion as a prognostic factor in early invasive adenocarcinoma of the cervix

Murakami I, Fujii T, Kameyama K, Iwata T, Saito M, Kubushiro , Aoki D

OBJECTIVE: The aim of this study was to investigate the risk and recurrence of early invasive adenocarcinoma of the cervix, and to determine whether non-radical methods of management could be...
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The Correlation of cervical intraepithelial neoplasia 3 detected by cervical punch biopsies with the pathologic results of conization and hysterectomy

Kim KW, Kim KM, Park JW, Jung HJ, Han JY, Kim JM, Park JH, Hwang SO, Lee WY, Song E

OBJECTIVE: To know the correlation of punch-biopsy proven cervical intraepithelial neoplasia (CIN) 3 with the results of cone and hysterectomy. METHODS: We reviewed the medical records from 1999 to 2008, retrospectively,...
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The safety of conization in the management of adenocarcinoma in situ of the uterine cervix

Kim ML, Hahn HS, Lim KT, Lee KH, Kim HS, Hong SR, Kim TJ

OBJECTIVE: To evaluate the occurrence of residual or recurrent disease after conization for adenocarcinoma in situ (AIS) of the uterine cervix. METHODS: Medical records of 99 patients with a histologically diagnosis...
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The analysis of factors which affect resection margin status after conization for cervical intraepithelial neoplasia

Jung CN, Oh NJ, Ryu KY, Oh HE, Kim WY

OBJECTIVE: The aim of this study was to evaluate the correlation between resection margin status after conization and severity of dysplasia and to evaluate the risk of residual disease and...
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Pregnancy Outcomes after Conservative Treatment of Cervical Intraepithelial Lesions: Cold Knife Conization and Loop Electrosurgical Procedure

Kim YY, Chae YH, An GH, Woo JH, Choi JS, Kim MH, Ryu HM, Choi KH, Han JY, Lee SW, Ahn HK, Yang JH, Kim MY

  • KMID: 1845269
  • Korean J Perinatol.
  • 2010 Sep;21(3):273-281.
OBJECTIVE: In this study, we evaluated whether different methods of conization of the cervix were associated with an increased risk of adverse pregnancy outcomes in subsequent pregnancy. METHODS: A retrospective case-control...
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The role of prophylactic cerclage in preventing preterm delivery after electrosurgical conization

Shin MY, Seo ES, Choi SJ, Oh SY, Kim BG, Bae DS, Kim JH, Roh CR

OBJECTIVE: To evaluate pregnancy outcomes after electrosurgical conization. METHODS: We retrospectively analyzed the outcomes of 56 singleton pregnancies after electrosurgical conization of the uterine cervix. Of the 56 cases, 25 women...
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Pregnancy outcome after cervical conization: risk factors for preterm delivery and the efficacy of prophylactic cerclage

Nam KH, Kwon JY, Kim YH, Park YW

OBJECTIVE: This study examined the risk factors for preterm birth and the efficacy of prophylactic cerclage in patients who had undergone cervical conization due to cervical intraepithelial neoplasia before pregnancy. METHODS:...
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Factors associated with HPV persistence after conization in patients with negative margins

Nam K, Chung S, Kim J, Jeon S, Bae D

OBJECTIVE: The clearance rate of human papillomavirus (HPV) after conization is generally high, although some HPV infections persist. We investigated the factors that affect the clearance of HPV after conization...
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