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Prediction of endotracheal tube size using a printed three-dimensional airway model in pediatric patients with congenital heart disease: a prospective, single-center, single-group study

Park S, Ahn J, Yoon SU, Choo KS, Kim HJ, Chung M, Kim HY

Background: To determine the correct size of endotracheal tubes (ETTs) for endotracheal intubation of pediatric patients, new methods have been investigated. Although the three-dimensional (3D) printing technology has been successful...
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Pre-contoured reconstruction plate fabricated via three-dimensional printed bending support

Song IS, Ryu JJ, Choi YJ, Lee UL

A mandibular continuity defect can be repaired using either a prosthetic device or autogenous bone. A titanium reconstruction plate can be used with a localized or vascularized flap over the...
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Utility of medical simulation in neurovascular critical care education

Mass-Ramírez S, Vergara-Burgos H, Sierra-Ochoa C, Lozada-Martinez ID, Moscote-Salazar LR, Janjua T, Rahman MM, Rahman S, Picón-Jaimes YA

Simulation has shown good results in medical scenarios in which the patient's problem can be solved by following protocols previously established in clinical practice guidelines. Therefore, the implementation of simulation...
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An Electronic Health Record-Integrated Computerized Intravenous Insulin Infusion Protocol: Clinical Outcomes and in Silico Adjustment

Park SW, Lee S, Cha WC, Hur KY, Kim JH, Lee MK, Park SM, Jin SM

BACKGROUND: We aimed to describe the outcome of a computerized intravenous insulin infusion (CII) protocol integrated to the electronic health record (EHR) system and to improve the CII protocol in...
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Comparing hemostatic resuscitation management of intraoperative massive bleeding with traumatic massive bleeding: a computer simulation

Lee YS, Kim KN, Lee MK, Sun JE, Lim HJ, Jun JH

Background: Appropriate blood component transfusion might differ between intraoperative massive bleeding and traumatic massive bleeding in the emergency department because trauma patients initially bleed undiluted blood and replacement typically lags...
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Integration of computer-simulated practical exercises into undergraduate medical pharmacology education at Mulungushi University, Zambia

Ezeala CC

Purpose: This study was conducted to determine whether a computer simulation of practical exercises in undergraduate medical pharmacology led to the realization of the intended learning outcomes. Methods: The study was...
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Clinical and pharmacological application of multiscale multiphysics heart simulator, UT-Heart

Okada JI, Washio T, Sugiura S, Hisada T

A heart simulator, UT-Heart, is a finite element model of the human heart that can reproduce all the fundamental activities of the working heart, including propagation of excitation, contraction, and...
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Finite element analysis of long-term changes of the breast after augmentation mammoplasty: Implications for implant design

Myung Y, Lee JG, Cho M, Heo CY

The development of breast implant technology continues to evolve over time, but changes in breast shape after implantation have not been fully elucidated. Thus, we performed computerized finite element analysis...
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Real-Color Volume Models Made from Real-Color Sectioned Images of Visible Korean

Chung BS, Park JS

BACKGROUND: Volume models made from magnetic resonance images on computed tomographs can produce horizontal, coronal, sagittal, and oblique planes that are used widely in clinics, although detailed structures cannot be...
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In Silico Model-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology

Agrawal R, Kalmady SV, Venkatasubramanian G

OBJECTIVE: Deficient brain-derived neurotrophic factor (BDNF) is one of the important mechanisms underlying the neuroplasticity abnormalities in schizophrenia. Aberration in BDNF signaling pathways directly or circuitously influences neurotransmitters like glutamate...
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Predictive performance of target controlled infusion of propofol-MCT/LCT using the modified Marsh and Schnider models: a simulation study

Lee JW, Choi BM, Noh GJ

BACKGROUND: Only two pharmacokinetic models of propofol are commercially available in the category of target controlled infusion (TCI) pumps: the modified Marsh and Schnider models. Both models were developed using...
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Application of Rapid Prototyping Technique and Intraoperative Navigation System for the Repair and Reconstruction of Orbital Wall Fractures

Cha JH, Lee YH, Ruy WC, Roe Y, Moon MH, Jung SG

BACKGROUND: Restoring the orbital cavity in large blow out fractures is a challenge for surgeons due to the anatomical complexity. This study evaluated the clinical outcomes and orbital volume after...
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In-Silico Trials for Glucose Control in Hospitalized Patients with Type 2 Diabetes

Choi K, Oh TJ, Lee JC, Kim M, Kim HC, Cho YM, Kim S

Although various basal-bolus insulin therapy (BBIT) protocols have been used in the clinical environment, safer and more effective BBIT protocols are required for glucose control in hospitalized patients with type...
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Drug Target Identification and Elucidation of Natural Inhibitors for Bordetella petrii: An In Silico Study

Rath SN, Ray M, Pattnaik A, Pradhan SK

Environmental microbes like Bordetella petrii has been established as a causative agent for various infectious diseases in human. Again, development of drug resistance in B. petrii challenged to combat against...
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Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on In Silico Modeling of Published Data

Shin GH, Kang BC, Jang DJ

Kimchi is a traditional Korean food prepared by fermenting vegetables, such as Chinese cabbage and radishes, which are seasoned with various ingredients, including red pepper powder, garlic, ginger, green onion,...
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Factors influencing the renal arterial Doppler waveform: a simulation study using an electrical circuit model (secondary publication)

Sung CK, Han BS, Kim SH

PURPOSE: The goal of this study was to evaluate the effect of vascular compliance, resistance, and pulse rate on the resistive index (RI) by using an electrical circuit model to...
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Clinical Application of Three-Dimensional Printing Technology in Craniofacial Plastic Surgery

Choi JW, Kim N

Three-dimensional (3D) printing has been particularly widely adopted in medical fields. Application of the 3D printing technique has even been extended to bio-cell printing for 3D tissue/organ development, the creation...
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A three-dimensional finite element analysis of the relationship between masticatory performance and skeletal malocclusion

Park JC, Shin HS, Cha JY, Park JT

PURPOSE: The aim of this study was to evaluate the transfer of different occlusal forces in various skeletal malocclusions using finite element analysis (FEA). METHODS: Three representative human cone-beam computed tomography...
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Concurrent and predictive validation of robotic simulator Tube 3 module

Kim JY, Kim SB, Pyun JH, Kim HK, Cho S, Lee JG, Kim JJ, Cheon J, Kang SH, Kang SG

PURPOSE: We previously described a new procedure specific module (Tube 3) to allow the practice of vesicourethral anastomosis after robot-assisted radical prostatectomy. Herein, we report a predetermined proficiency level of...
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In silico analysis for identifying potential vaccine candidates against Staphylococcus aureus

Delfani S, Imani Fooladi AA, Mobarez AM, Emaneini M, Amani J, Sedighian

PURPOSE: Staphylococcus aureus is one of the most important causes of nosocomial and community-acquired infections. The increasing incidence of multiple antibiotic-resistant S. aureus strains and the emergence of vancomycin resistant...
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