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Effects of the Advanced Practice Nurse-Led Psychoeducational Program for Colorectal Cancer Survivors

Kim HK, Yoo YS

Purpose: This study aimed to investigate the effects of an advanced practice nurse-led psychoeducational program on distress, anxiety, depression, coping with cancer (CWC), health promotion behavior (HPB), and quality of...
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Minimally invasive surgery for colorectal cancer, a look back to look forward: a personal history

Choi GS

While laparoscopic colonoscopy was reported by several surgeons in the early 1990s, laparoscopic colorectal surgery has been attempted sporadically since 1992 in Korea. Then, in 2000, the Korean Laparoscopic Colorectal...
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Short-Term Impact of Temporary Shutdown of a University-Affiliated Hospital on Patients With Colorectal Cancer During the Coronavirus Disease 2019 Pandemic

Park YY, Lee J, Lee Ky, Oh ST

Owing to in-hospital transmission of coronavirus disease 2019 (COVID-19), Uijeongbu St. Mary’s Hospital, a university-affiliated hospital in South Korea, was temporarily closed for disinfection in March 2020. This study aimed to...
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Prognostic and clinicopathological significance of Fusobacterium nucleatum in colorectal cancer: a systemic review and meta-analysis

Kim Y, Cho NY, Kang GH

Background: Fusobacterium nucleatum has been identified to promote tumor progression in colorectal cancer (CRC). However, association between F. nucleatum and prognostic or clinicopathological features has been diverse among studies, which...
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Feasibility and safety of endoscopic submucosal dissection for lesions in proximity to a colonic diverticulum

Ikezawa N, Toyonaga T, Tanaka S, Yoshizaki T, Takao T, Abe H, Sakaguchi H, Tsuda K, Urakami S, Nakai T, Harada T, Miura K, Yamasaki T, Kostalas S, Morita Y, Kodama Y

Background/Aims: Endoscopic submucosal dissection (ESD) for diverticulum-associated colorectal lesions is generally contraindicated because of the high risk of perforation. Several studies on patients with such lesions treated with ESD have...
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Does computer-aided diagnostic endoscopy improve the detection of commonly missed polyps? A meta-analysis

Sivananthan A, Nazarian S, Ayaru L, Patel K, Ashrafian H, Darzi A, Patel N

Background/Aims: Colonoscopy is the gold standard diagnostic method for colorectal neoplasia, allowing detection and resection of adenomatous polyps; however, significant proportions of adenomas are missed. Computer-aided detection (CADe) systems in...
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Association of Physical Activity and Sedentary Behavior With the Risk of Colorectal Cancer

An S, Park S

Background: Although recent evidence supports that prolonged sedentary behavior and reduced physical activity are associated with colorectal cancer risk, there are few studies analyzing the colorectal cancer risk according to...
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Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer

Jun H, Lee J, Lee HA, Kim SE, Shim KN, Jung HK, Jung SA, Moon CM

Background/Aims: The relationship between fasting blood glucose (FBG) variability and colorectal cancer (CRC) remains ill-defined. This study aimed to evaluate the association of FBG variability with CRC risk in the...
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Current status of robotic surgery for colorectal cancer: A review

Jung WB

The number of robot-assisted colorectal surgeries is increasing because these robotic devices afford surgeon-controlled, high-definition, and threedimensional vision during surgery and have sophisticated, angulated arms with remarkable ergonomics and a...
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Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer

Ki S, Cho Y, Choi Y, Lim S, Kim M, Lee J

Background: The depth of anesthesia is an essential factor in surgical prognosis. The neurotoxic effect of chemotherapeutic drugs affects the sensitivity to anesthetics. This study was conducted to determine whether...
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A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis

Zeng J, Xiao Xq, Zhou Zy

Purpose Emerging evidence has shown that SKP1-cullin-1-F-box-protein (SCF) E3 ligases contribute to the pathogenesis of different cancers by mediating the ubiquitination and degradation of tumor suppressors. However, the functions of SCF...
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Machine Learning Model for Predicting Postoperative Survival of Patients with Colorectal Cancer

Osman MH, Mohamed RH, Sarhan HM, Park EJ, Baik SH, Lee KY, Kang J

Purpose Machine learning (ML) is a strong candidate for making accurate predictions, as we can use large amount of data with powerful computational algorithms. We developed a ML based model...
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Effectiveness and early postoperative outcomes of palliative endoluminal stenting versus Hartmann’s procedure in acute malignant bowel obstruction in high-risk patients

Mahfouz MF, Salama TMS, Afifi AH, Dabous HMK

Purpose: The emergency intervention for acute malignant left-sided colonic obstruction remains controversial. Conflicting reports exist regarding the efficacy and safety of endoscopic placement of self-expandable metallic stents (SEMS) vs. primary...
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Protocatechuic Acid, a Gut Bacterial Metabolite of Black Raspberries, Inhibits Adenoma Development and Alters Gut Microbiome Profiles in Apc Min/+ Mice

Dong A, Lin CW, Echeveste CE, Huang YW, Oshima K, Yearsley M, Chen X, Yu J, Wang LS

Administration of black raspberries (BRBs) and their anthocyanin metabolites, including protocatechuic acid (PCA), has been demonstrated to exert chemopreventive effects against colorectal cancer through alteration of innate immune cell trafficking,...
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Dome-type carcinoma of the rectum mimicking a submucosal tumor: a case report and literature review

Noh BJ, Park SJ, Jang JY, Kim YW

Dome-type carcinoma (DC) has been recognized as a rare variant of adenocarcinoma, which arises in gutassociated lymphoid tissue. It has a specific morphologic feature of a dome-like protrusion associated with...
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Colorectal adenocarcinoma with enteroblastic differentiation: diagnostic challenges of a rare case encountered in clinical practice

Abada E, Anaya IC, Abada O, Lebbos A, Beydoun R

Colorectal adenocarcinoma with enteroblastic differentiation (CAED) is a rare subtype of colonic adenocarcinoma characterized by increased α-fetoprotein (AFP) production and the expression of at least one enteroblastic marker including AFP,...
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Prevalence and associated risk of advanced colorectal neoplasia in adults with sarcopenia

Kim MC, Kim KO, Kang MK

Background/Aims: Although several studies have shown that sarcopenia is associated with poor outcomes in colorectal cancer patients, the impact of sarcopenia on the development of colorectal neoplasia remains unclear. We...
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Positive fecal immunochemical test results are associated with non-colorectal cancer mortality

Jung YS, Lee J, Moon CM

Background/Aims: Studies have reported an association between fecal occult blood and increased all-cause, non-colorectal cancer (CRC) as well as CRC mortality. This study aimed to determine whether positive fecal immunochemistry...
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Clinical Characteristics and Long-term Outcomes of Pediatric Ulcerative Colitis: A Single-Center Experience in Korea

Jang J, Lee SH, Jeong IS, Cho J, Kim HJ, Oh SH, Kim DY, Lee HS, Park SH, Ye BD, Yang SK, Kim KM

Background/Aims: Although pediatric ulcerative colitis (UC) has a different phenotype and clinical course than adult UC, its clinical features and outcomes are poorly defined, especially in Asian populations. This study...
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Surgical Strategy for Primary Colorectal Carcinoma and Synchronous Pulmonary Metastasis Resection

Kim TY, Cho JH, Choi YS, Kim HK, Kim JG, Shim YM

Background: The surgical strategy for single-stage resection of primary colorectal cancer (CRC) and synchronous pulmonary metastases remains a matter of debate. Methods: Perioperative data of patients who underwent single-stage resection of...
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