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Immunohistochemical Analysis of Nuclear Factor, p38, and Cyclin D1 Proteins in Premalignant Lesions and Carcinomas of the Colorectal Mucosa

Lee SD, Lee TJ, Park ES

  • KMID: 783112
  • Korean J Gastroenterol.
  • 2008 Dec;52(6):359-367.
BACKGROUND/AIMS: Nuclear factor-kappa B p65 (NF-kappa B p65), nuclear factor-kappa B1 p50 (NF-kappa B p50) have been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis....
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p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells

Park KS, Jeon SH, Oh JW, Choi KY

  • KMID: 1103323
  • Exp Mol Med.
  • 2004 Dec;36(6):557-562.
p21Cip/WAF1, an important regulator of cell proliferation, is induced by both p53- and extracellular signal regulated kinase (ERK) pathways. The induction of p21Cip/WAF1 occurs by prolonged activation of the ERKs...
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