- Cyclooxygenase-2 Expression according to Size and Location of Gastric and Colorectal Tubular Adenomas
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Kim SH, Lee JH, Kang KH, Park JH, Park CK, Cho CM, Kweon YO, Kim SK, Choi YH, Bae HI, Kim MS
- KMID: 1113421
- Korean J Gastroenterol.
- 2004 Oct;44(4):206-211.
BACKGROUND/AIMS: Recent studies have shown that cyclooxygenase-2 (COX-2) may be involved in the process of invasion, growth and apoptosis in colorectal carcinoma and in the growth and tumorigenesis in... -
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- Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma
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Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ
- KMID: 1731316
- J Korean Med Sci.
- 1999 Aug;14(4):417-423.
- doi: 10.3346/jkms.1999.14.4.417
Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial... -
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- Immunohistochemical Analysis of Nuclear Factor, p38, and Cyclin D1 Proteins in Premalignant Lesions and Carcinomas of the Colorectal Mucosa
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Lee SD, Lee TJ, Park ES
- KMID: 783112
- Korean J Gastroenterol.
- 2008 Dec;52(6):359-367.
BACKGROUND/AIMS: Nuclear factor-kappa B p65 (NF-kappa B p65), nuclear factor-kappa B1 p50 (NF-kappa B p50) have been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis.... -
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- p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells
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Park KS, Jeon SH, Oh JW, Choi KY
- KMID: 1103323
- Exp Mol Med.
- 2004 Dec;36(6):557-562.
p21Cip/WAF1, an important regulator of cell proliferation, is induced by both p53- and extracellular signal regulated kinase (ERK) pathways. The induction of p21Cip/WAF1 occurs by prolonged activation of the ERKs... -
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- Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells
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Hwang WC, Kim MK, Song JH, Choi KY, Min DS
- KMID: 2155389
- Exp Mol Med.
- 2014 Dec;46(12):e124.
- doi: 10.1038/emm.2014.74
Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase... -
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