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Clinical Implications of Microsatellite Instability in T1 Colorectal Cancer

Kang J, Lee HW, Kim IK, Kim NK, Sohn SK, Lee KY

PURPOSE: The estimation of regional lymph node metastasis (LNM) risk in T1 colorectal cancer is based on histologic examination and imaging of the primary tumor. High-frequency microsatellite instability (MSI-H) is...
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Clinicopathologic Impacts of Poorly Differentiated Cluster-Based Grading System in Colorectal Carcinoma

Kim JW, Shin MK, Kim BC

Differentiation-based histologic grading of colorectal carcinoma (CRC) is widely used, but its clinical impact is limited by insufficient prognostic value, interobserver disagreement, and the difficulty of its application to CRC...
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