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p53 mutation in patients with ulcerative colitis in rectal biopsy

Kim HJ, Chang SK

  • KMID: 759070
  • Korean J Intern Med.
  • 1998 Jul;13(2):110-116.
OBJECTIVES: Long standing ulcerative colitis (UC) has been known to be one of the precancerous diseases of colorectal cancer. Although the frequent loss of p53 allele (LOH) and aneuploidy were...
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Intravenous KITENIN shRNA Injection Suppresses Hepatic Metastasis and Recurrence of Colon Cancer in an Orthotopic Mouse Model

Hwang JE, Shim HJ, Park YK, Cho SH, Bae WK, Kim DE, Kim KK, Chung IJ

KITENIN (KAI1 C-terminal interacting tetraspanin) promotes invasion and metastasis in mouse colon cancer models. In the present study, we evaluated the effects of KITENIN knockdown by intravenous administration of short...
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Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells

Lee E, Choi MK, Han IO, Lim SJ

  • KMID: 1094159
  • Exp Mol Med.
  • 2006 Jun;38(3):325-331.
SC-560, a strucutral analogue of celecoxib, induces growth inhibition in a wide range of human cancer cells in a cyclooxygenase (COX)-independent manner. Since SC-560 suppresses the growth of cancer cells...
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