- Frequent Epigenetic Inactivation of XAF1 by Promotor Hypermethylation in Human Colon Cancers
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Jang JY, Kim HJ, Chi SG, Lee KY, Nam KD, Kim NH, Lee SK, Joo KR, Dong SH, Kim BH, Chang YW, Lee JI, Chang R
- KMID: 772766
- Korean J Gastroenterol.
- 2005 Apr;45(4):285-293.
BACKGROUND/AIMS: X-linked inhibitor of apoptosis (XIAP) is the most potent member of the IAP family that exerts antiapoptotic effects. Recently, XIAP-associated factor 1 (XAF1) and two mitochondrial proteins, Smac/DIABLO... -
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- Field Cancerization in Sporadic Colon Cancer
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Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI
- KMID: 2412075
- Gut Liver.
- 2016 Sep;10(5):773-780.
- doi: 10.5009/gnl15334
BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4... -
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- Gene transfer using liposome-complexed adenovirus seems to overcome limitations due to coxsackievirus and adenovirus receptor-deficiency of cancer cells, both in vitro and in vivo
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Han SY, Lee YJ, Jung HI, Lee SW, Lim SJ, Hong SH, Jeong JS
- KMID: 1094122
- Exp Mol Med.
- 2008 Aug;40(4):427-434.
- doi: 10.3858/emm.2008.40.4.427
Use of adenoviruses as vehicle for gene therapy requires that target cells express appropriate receptors such as coxsakievirus and adenovirus receptor (CAR). We show here that CAR-deficiency in cancer cells,... -
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- Effects of Chromosomal Polyploidy on Survival of Colon Cancer Cells
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Park SU, Choi ES, Jang YS, Hong SH, Kim IH, Chang DK
- KMID: 1128353
- Korean J Gastroenterol.
- 2011 Mar;57(3):150-157.
- doi: 10.4166/kjg.2011.57.3.150
BACKGROUND/AIMS: Tetraploid cells are frequently observed in the inflamed mucosal epithelial cells of the patients with Barrett's esophagus or chronic ulcerative colitis. Polyploidy often occurs during cell fusion, abortive cell... -
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