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Salmonella penetrates the basement membrane of intestinal epithelial cells into deeper tissues, in which process extracellular matrix proteases should be required. Hypothesizing that the proteases might be provided by...
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9),
which degrade extracellular matrix, are believed to play a crucial role in tumor
invasion and metastasis. Angiogenesis is also perceived as an important...
The matrix metalloproteinases (MMPs) have been associated with tumor cell
invasion and metastasis of human cancers by mediating the degradation of
extracellular matrix components. Therefore, these enzymes and their...