- Effect of growth hormone releasing hormone on chondrocytes of osteoarthritis
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LI Z, LI Y
- KMID: 2524257
- Korean J Intern Med.
- 2022 Jan;37(1):222-229.
- doi: 10.3904/kjim.2018.399
Background/Aims: To evaluate the effect and possible mechanism of growth hormone releasing hormone (GHRH) on chondrocytes of osteoarthritis (OA). Methods: Articular chondrocytes were cultured and the expression of GHRH receptor in... -
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- Associations of COL2A1 Gene Polymorphisms and Ankylosing Spondylitis in the Korean Population
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Son ES, Um SH, Youn MY
- KMID: 2503665
- J Korean Soc Spine Surg.
- 2020 Mar;27(1):1-8.
- doi: 10.4184/jkss.2020.27.1.1
With highly active antiretroviral therapy, human immunodeficiency virus (HIV) infection is considered to be a manageable chronic disease. The improved prognosis increases the desire of individuals with HIV to have... -
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- De novo mutations in COL4A5 identified by whole exome sequencing in 2 girls with Alport syndrome in Korea
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Han KH, Park JE, Ki CS
- KMID: 2451970
- Korean J Pediatr.
- 2019 May;62(5):193-197.
- doi: 10.3345/kjp.2018.06772
Alport syndrome (ATS) is an inherited glomerular disease caused by mutations in one of the type IV collagen novel chains (α3, α4, and α5). ATS is characterized by persistent microscopic... -
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- Age-related Reference Intervals for Total Collagen-I-N-terminal Propeptide in Healthy Korean Population
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Yoo JI, Park AJ, Lim YK, Kweon OJ, Choi JH, Do JH, Kim S, Kim Y, Ha YC
- KMID: 2427989
- J Bone Metab.
- 2018 Nov;25(4):235-241.
- doi: 10.11005/jbm.2018.25.4.235
BACKGROUND: Procollagen type I N-terminal propeptide (PINP) is one of the most clinically useful bone formation biomarkers. Therefore, the purpose of this study was to independently evaluate the performance of... -
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- A Novel Method to Study the Effects of Cyclosporine on Gingival Overgrowth in Children
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Han K, Kim J
- KMID: 2438313
- J Korean Acad Pediatr Dent.
- 2018 Aug;45(3):271-279.
- doi: 10.5933/JKAPD.2018.45.3.271
Previous studies to elucidate the etiology of cyclosporine(Cs)-induced gingival overgrowth in children have not completely excluded all factors that may cause differences among individuals. This study examined the effect of... -
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- Heparin/Collagen 3D Scaffold Accelerates Hepatocyte Differentiation of Wharton's Jelly-Derived Mesenchymal Stem Cells
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Aleahmad F, Ebrahimi S, Salmannezhad M, Azarnia M, Jaberipour M, Hoseini M, Talaei-Khozani T
- KMID: 2394978
- Tissue Eng Regen Med.
- 2017 Aug;14(4):443-452.
- doi: 10.1007/s13770-017-0048-z
Both mature and stem cell-derived hepatocytes lost their phenotype and functionality under conventional culture conditions. However, the 3D scaffolds containing the main extracellular matrix constitutions, such as heparin, may provide... -
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- Low-Level Light Therapy with 410 nm Light Emitting Diode Suppresses Collagen Synthesis in Human Keloid Fibroblasts: An In Vitro Study
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Lee HS, Jung SE, Kim SK, Kim YS, Sohn S, Kim YC
- KMID: 2394837
- Ann Dermatol.
- 2017 Apr;29(2):149-155.
- doi: 10.5021/ad.2017.29.2.149
BACKGROUND: Keloids are characterized by excessive collagen deposition in the dermis, in which transforming growth factor β (TGF-β)/Smad signaling plays an important role. Low-level light therapy (LLLT) is reported as... -
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- Effects of gangliosides from deer bone extract on the gene expressions of matrix metalloproteinases and collagen type II in interleukin-1β-induced osteoarthritic chondrocytes
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Suh HJ, Lee H, Min BJ, Jung SU, Jung EY
- KMID: 2359612
- Nutr Res Pract.
- 2016 Dec;10(6):569-574.
- doi: 10.4162/nrp.2016.10.6.569
BACKGROUND/OBJECTIVES: We investigated the anti-osteoarthritic effects of deer bone extract on the gene expressions of matrix metalloproteinases (MMPs) and collagen type II (COL2) in interleukin-1β-induced osteoarthritis (OA) chondrocytes. MATERIALS/METHODS: Primary rabbit... -
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- Alginate-Hyaluronic Acid-Collagen Composite Hydrogel Favorable for the Culture of Chondrocytes and Their Phenotype Maintenance
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Mahapatra , Jin GZ, Kim HW
- KMID: 2360802
- Tissue Eng Regen Med.
- 2016 Oct;13(5):538-546.
- doi: 10.1007/s13770-016-0059-1
Articular cartilage has limited regeneration capacity, thus significant challenge has been made to restore the functions. The development of hydrogels that can encapsulate and multiply cells, and then effectively maintain... -
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- Dermatofibrosarcoma Protuberans: A Study of Clinical, Pathologic, Genetic, and Therapeutic Features in Korean Patients
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Zheng Z, Piao J, Lee JH, Kim SE, Kim SC, Chung KY, Roh MR
- KMID: 2070022
- Yonsei Med J.
- 2015 Mar;56(2):440-446.
- doi: 10.3349/ymj.2015.56.2.440
PURPOSE: Dermatofibrosarcoma protuberans (DFSP) carries a translocation resulting in the collagen type I alpha 1 (COL1A1)-platelet-derived growth factor beta (PDGFB) fusion gene, which is responsible for PDGFB activation. The purpose... -
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- The Effects of Botulinum Toxin A on Collagen Synthesis, Expression of MMP (matrix metalloproteinases)-1,2,9 and TIMP (tissue inhibitors of metalloproteinase)-1 in the Keloid Fibroblasts
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Roh TS, Hong JW, Lee WJ, Yoo HS, Lew DH, Kim YS
- KMID: 2266920
- Arch Aesthetic Plast Surg.
- 2013 Jun;19(2):114-119.
- doi: 10.14730/aaps.2013.19.2.114
Keloids are characterized by excessive extracelluar matrix (ECM) deposition such as collagen, fibronectin, elastin, and proteoglycans in the dermis. Recently, the use of botulinum toxin A (BTXA) in the treatment... -
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- Effect of Combined Sex Hormone Replacement on Bone/Cartilage Turnover in a Murine Model of Osteoarthritis
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Yang JH, Kim JH, Lim DS, Oh KJ
- KMID: 1392987
- Clin Orthop Surg.
- 2012 Sep;4(3):234-241.
- doi: 10.4055/cios.2012.4.3.234
BACKGROUND: Estrogens act on estrogen receptors distributed in articular cartilages, synovial membrane, and ligaments, which are thought to be related with degenerative changes. Meanwhile, progesterone is known to have a... -
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- Clinical study of correlation between C-terminal cross-linking telopeptide of type I collagen and risk assessment, severity of disease, healing after early surgical intervention in patients with bisphophonate-related osteonecrosis of the jaws
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Song JW, Kim KH, Song JM, Chun BD, Kim YD, Kim UK, Shin SH
- KMID: 2189799
- J Korean Assoc Oral Maxillofac Surg.
- 2011 Feb;37(1):1-8.
- doi: 10.5125/jkaoms.2011.37.1.1
INTRODUCTION: The utility of the C-terminal cross-linking telopeptide test (CTX) as a method for staging Bisphosphonate-related osteonecrosis of the jaws (BRONJ) and its healing process was examined. MATERIALS AND METHODS: A... -
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- 2-Deoxy-D-glucose regulates dedifferentiation through beta-catenin pathway in rabbit articular chondrocytes
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Yu SM, Kim HA, Kim SJ
- KMID: 1104210
- Exp Mol Med.
- 2010 Jul;42(7):503-513.
- doi: 10.3858/emm.2010.42.7.051
2-deoxy-D-glucose (2DG) is known as a synthetic inhibitor of glucose. 2DG regulates various cellular responses including proliferation, apoptosis and differentiation by regulation of glucose metabolism in cancer cells. However, the... -
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- Comparison of Left Ventricular Hypertrophy, Fibrosis and Dysfunction According to Various Disease Mechanisms such as Hypertension, Diabetes Mellitus and Chronic Renal Failure
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Koh YS, Jung HO, Park MW, Baek JY, Yoon SG, Kim PJ, Ihm SH, Chang K, Oh YS, Youn HJ, Baek SH, Chung WS, Seung KB, Kim JH
- KMID: 1473715
- J Cardiovasc Ultrasound.
- 2009 Dec;17(4):127-134.
- doi: 10.4250/jcu.2009.17.4.127
BACKGROUND: Left ventricular hypertrophy (LVH) has been known as an important predictor of prognosis of cardiovascular disease. Carboxy-terminal propeptide of procollagen type I (PIP) is related with myocardial fibrosis. We... -
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- Regulation of Type IV Collagen alpha Chains of Glomerular Epithelial Cells in Diabetic Conditions
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Ha TS, Hong EJ, Ahn EM, Ahn HY
- KMID: 1782003
- J Korean Med Sci.
- 2009 Oct;24(5):837-843.
- doi: 10.3346/jkms.2009.24.5.837
An early feature of diabetic nephropathy is the alteration of the glomerular basement membrane (GBM), which may result in microalbuminuria, subsequent macroproteinuria, and eventual chronic renal failure. Although type IV... -
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- Preventive Effect of Pentoxifylline on Cyclosporine A-Induced Collagen Synthesis in Calf Pulmonary Artery Endothelial Cells
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Kim SE, Sung YH, Shin MS, Kim CJ, Park JH, Lee BJ, Yi JW, Han SY
- KMID: 2096534
- J Korean Surg Soc.
- 2009 Mar;76(3):135-143.
- doi: 10.4174/jkss.2009.76.3.135
PURPOSE: Cyclosporine A (CsA) is a potent immunosuppressive agent, and it has been used to prevent rejection of transplanted organs and to treat autoimmune diseases. Many side effects of CsA,... -
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- Ectopic expression of cyclooxygenase-2-induced dedifferentiation in articular chondrocytes
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Lee WK, Yu SM, Cheong SW, Sonn JK, Kim SJ
- KMID: 1072952
- Exp Mol Med.
- 2008 Dec;40(6):721-727.
- doi: 10.3858/emm.2008.40.6.721
Cyclooxygenase-2 (COX-2) is known to modulate bone metabolism, including bone formation and resorption. Because cartilage serves as a template for endochondral bone formation and because cartilage development is initiated by... -
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- The expression of MMP-1, -8, and -13 mRNA in the periodontal ligament of rats during tooth movement with cortical punching
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Gwack C, Kim SS, Park SB, Son WS, Kim YD, Jun ES, Park MH
- KMID: 1975907
- Korean J Orthod.
- 2008 Jun;38(3):187-201.
- doi: 10.4041/kjod.2008.38.3.187
OBJECTIVE: The aim of this study was to determine whether cortical punching stimulates the expression of matrix metalloproteinase-1, -8, and -13 in orthodontic tooth movement in rats. METHODS: A total... -
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- Effect of cultured chondrocyte-seeded chondroitin-sulfate conjugated type I collagen scaffold on cartilage regeneration
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Lim JJ, Son D, Sohn K, Yang E, Han K
- KMID: 2040880
- J Korean Soc Plast Reconstr Surg.
- 2007 Jul;34(4):413-419.
PURPOSE: In this study, porous type I collagen scaffolds were cross-linked using dehydrothermal(DHT) treatment and/or 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide(EDC), in the presence and absence of chondroitin-6-sulfate(CS) and cultured autologous chondrocytes(Chondro) for... -
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