- TGF-beta-treated antigen presenting cells suppress collagen-induced arthritis through the promotion of Th2 responses
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Jung S, Park YK, Lee H, Shin JH, Lee GR, Park SH
- KMID: 946651
- Exp Mol Med.
- 2010 Mar;42(3):187-194.
- doi: 10.3858/emm.2010.42.3.019
Collagen-induced arthritis (CIA) is mediated by self-reactive CD4+ T cells that produce inflammatory cytokines. TGF-beta2-treated tolerogenic antigen-presenting cells (Tol-APCs) are known to induce tolerance in various autoimmune diseases. In this... -
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- The requirement of natural killer T-cells in tolerogenic APCs-mediated suppression of collagen-induced arthritis
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Jung S, Park YK, Shin JH, Lee H, Kim SY, Lee GR, Park SH
- KMID: 1104381
- Exp Mol Med.
- 2010 Aug;42(8):547-554.
- doi: 10.3858/emm.2010.42.8.055
TGF-beta-induced tolerogenic-antigen presenting cells (Tol-APCs) could induce suppression of autoimmune diseases such as collagen-induced arthritis (CIA) and allergic asthma. In contrast, many studies have shown that NKT cells are involved... -
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