- Phenotypic Characterization of Ligamentum Flavum Cells from Patients with Ossification of Ligamentum Flavum
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Zhong ZM, Chen JT
- KMID: 1758565
- Yonsei Med J.
- 2009 Jun;50(3):375-379.
- doi: 10.3349/ymj.2009.50.3.375
PURPOSE: The objective of this study was to determine the phenotypic characterization of ligamentum flavum cells from patients with ossification of the ligamentum flavum (OLF). MATERIALS AND METHODS: Ligamentum flavum... -
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- Snapshot of degenerative aging of porcine intervertebral disc: a model to unravel the molecular mechanisms
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Cho H, Park SH, Lee S, Kang M, Hasty KA, Kim SJ
- KMID: 1107374
- Exp Mol Med.
- 2011 Jun;43(6):334-340.
- doi: 10.3858/emm.2011.43.6.036
Larger animal models, such as porcine, have been validated as appropriate models of the human disc with respect to biomechanics and biochemistry. They are advantageous for research as the models... -
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- Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
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Chen B, Qin J, Wang H, Magdalou J, Chen L
- KMID: 964663
- Exp Mol Med.
- 2010 Oct;42(10):684-695.
- doi: 10.3858/emm.2010.42.10.067
The study investigated the effects of adenovirus-mediated gene transfection of basic fibroblast growth factor (bFGF), bFGF combined with interleukin-1 receptor antagonist protein (IL-Ra) and/or insulin-like growth factor-1 (IGF-1) both in... -
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- Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
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Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE
- KMID: 2352817
- Yonsei Med J.
- 2015 Jan;56(1):277-286.
- doi: 10.3349/ymj.2015.56.1.277
PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs... -
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