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Pediatric postintensive care syndrome: high burden and a gap in evaluation tools for limited-resource settings

Chaiyakulsil C, Opasatian R, Tippayawong P

This article aimed to summarize the impact and burden of pediatric postintensive care syndrome (PICS-p) in the physical, mental, cognitive, and social health domains after a review of the current...
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Validity of the Montreal Cognitive Assessment (MoCA) Index Scores: a Comparison with the Cognitive Domain Scores of the Seoul Neuropsychological Screening Battery (SNSB)

Kim H, Yu KH, Lee BC, Kim BC, Kang Y

Background and Purpose: A new approach was proposed to score the Montreal Cognitive Assessment (MoCA) index scores for 6 cognitive domains: orientation (OIS), attention (AIS), language (LIS), visuospatial function (VIS),...
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Effects of Virtual Reality-Based Cognitive Training in the Elderly with and without Mild Cognitive Impairment

Maeng S, Hong JP, Kim WH, Kim H, Cho SE, Kang JM, Na KS, Oh SH, Park JW, Bae JN, Cho SJ

Objective This study aimed to introduce a 4-week long fully immersive virtual reality-based cognitive training (VRCT) program that could be applied for both a cognitively normal elderly population and patients...
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Neurodevelopmental outcomes of very low birth weight infants in the Neonatal Research Network of Japan: importance of neonatal intensive care unit graduate follow-up

Kono Y, on behalf of the Neonatal Research Network of Japan

Here we describe the neurodevelopmental outcomes of very low birth weight (VLBW) infants (birth weight ≤1,500 g) at 3 years of age in the Neonatal Research Network of Japan (NRNJ)...
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Effects of Tai Chi Exercise Program on Cognitive Function among Older Adults at Risk for Dementia Living in Rural Areas

Song R, Ju K, Jung MS, Kim H, Fan X

Purpose: This study aimed to examine the effects of the Tai Chi exercise program on cognitive function among older adults at risk of dementia living in rural areas. Methods: A...
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Association of Cardiovascular Disease Risk and Physical Fitness with Cognitive Impairment in Korean Elderly Women

Lee I, Kang H

Purpose: This study aimed to investigate the effect of cardiovascular disease (CVD) risk and physical fitness on cognitive impairment in Korean elderly women. Methods: In a cross-sectional design, a total of...
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Early Detection of Mild Cognitive Impairment Using Visual Immediate Recall Test in the Community

Choo IH

Objective: Mild cognitive impairment (MCI) is transitional state between cognitively normal and dementia. It is not easy to detect MCI patient early in the community. This study aimed to detect...
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Predicting Mild Cognitive Impairment to Alzheimer’s Disease Transition: Role of Instrumental Activities of Daily Living

Woo SK, Bae S, Kim JH, Kim DK

Objective: This study aimed to investigate the association with the functioning of instrumental-activities of daily living (I-ADL) and future development of Alzheimer’s disease (AD) in persons with mild cognitive impairment...
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Correlation between fish consumption and the risk of mild cognitive impairment in the elderly living in rural areas

Yu A, Kim J, Choi BY, Kim MK, Yang Y, Yang YJ

Purpose: This study examines the correlation between fish consumption and the risk of mild cognitive impairment in the elderly living in rural areas. Methods: The Yangpyeong cohort data collected from Yangpyeong...
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Evaluation of Reproducibility of Brain Volumetry between Commercial Software, Inbrain and Established Research Purpose Method, FreeSurfer

J, JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Background and Purpose We aimed to determine the intermethod reproducibility between the commercial software Inbrain (MIDAS IT) and the established research-purpose method FreeSurfer, as well as the effect of MRI...
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Relationship between Hearing Loss and Dementia Differs According to the Underlying Mechanism

Jung J, Bae SH, Han JH, Kwak SH, Nam GS, Lee PH, Sohn YH, Yun M, Ye BS

Background and Purpose The associations between hearing loss (HL) and the mechanisms underlying cognitive impairment (CI) remain unclear. We evaluated the effects of clinical factors, vascular magnetic resonance imaging (MRI)...
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Comprehensive Visual Rating Scale on Magnetic Resonance Imaging: Application to Prodromal Alzheimer Disease

Chung JK, Jang JW, the Alzheimer’s Disease Neuroimaging Initiative

Background: A comprehensive visual rating scale (CVRS) using brain magnetic resonance imaging (MRI) was previously developed to evaluate structural changes in the brains of older patients. This study investigated the...
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Comparison of Automated Brain Volume Measures by NeuroQuant vs. Freesurfer in Patients with Mild Cognitive Impairment: Effect of Slice Thickness

Yim Y, Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Purpose: This study aimed to examine the inter-method reliability and volumetric differences between NeuroQuant (NQ) and Freesurfer (FS) using T1 volume imaging sequence with different slice thicknesses in patients with...
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Is Korea Prepared for an Alzheimer’s Disease-Modifying Therapy? Assessing the Korean Healthcare System Infrastructure and the Effect of Blood-Based Biomarker Tests

Jun H, Cho SK, Yoong J, Mattke S

Background: With the rapid demographic change in Korea, Alzheimer’s disease has become a primary concern. Recent developments in disease-modifying therapies provide hope that therapy may become available soon. The high...
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Prenatal Exposure to High Cortisol Induces ADHD-like Behaviors with Delay in Spatial Cognitive Functions during the Post-weaning Period in Rats

Jeon SC, Kim HJ, Ko EA, Jung SC

High levels of cortisol in blood are frequently observed in patients with major depressive disorders and increased cortisol level induces depressivelike symptoms in animal models. However, it is still unclear...
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Trough Melatonin Levels Differ between Early and Late Phases of Alzheimer Disease

Lin CH, Chiu CC, Lane HY

Objective: Melatonin has been considered to have an essential role in the pathophysiology of Alzheimer’s disease (AD) for its regulatory function on circadian rhythm and interaction with glutamate for the...
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Structural Changes in the Hippocampal Subfields in Early-Onset Mild Cognitive Impairment

Moon SW, Yoo DY

  • KMID: 2513157
  • J Korean Soc Biol Ther Psychiatry.
  • 2021 Feb;27(1):67-73.
Objectives:The aim of this study was to examine the structural change in the hippocampal subfields in early-onset (EO) mild cognitive impairment (MCI) patients associated with the APOE ε4 carrier state. Methods:This...
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Development of Random Forest Algorithm Based Prediction Model of Alzheimer’s Disease Using Neurodegeneration Pattern

Kim J, Lee M, Lee MK, Wang SM, Kim NY, Kang DW, Um YH, Na HR, Woo YS, Lee CU, Bahk WM, Kim D, Lim HK

Objective Alzheimer’s disease (AD) is the most common type of dementia and the prevalence rapidly increased as the elderly population increased worldwide. In the contemporary model of AD, it is...
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The Association of Blood-Based Inflammatory Factors IL-1β, TGF-β and CRP with Cognitive Function in Alzheimer’s Disease and Mild Cognitive Impairment

Park JK, Lee KJ, Kim JY, Kim H

Objective Many patients suffer from dementia in its most common form, Alzheimer’s disease (AD). In this study, the levels of IL-1β, TGF-β and CRP, which are involved in the inflammatory...
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The Expanded Disability Status Scale Score and Demographic Indexes Are Correlated with the Severity of Cognitive Impairment in Multiple Sclerosis Patients

Sadigh-Eteghad S, Garravnd NA, Feizollahi M, Talebi M

Background and Purpose Cognitive impairment (CI) is a common symptom of multiple sclerosis (MS). Although demographic and clinical factors contribute to MS-dependent CI, previous findings have been inconsistent. This study...
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