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Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes

Lim HS, Jin S, Yun SJ

As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and...
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