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Effects of prematuration culture with a phosphodiesterase-3 inhibitor on oocyte morphology and embryo quality in in vitro maturation

Cheruveetil MA, Shetty PK, Rao KA, Rajendran A, Asif M

Objective: The study assessed the developmental potential of germinal vesicle (GV) oocytes subjected to in vitro maturation (IVM) after prematuration culture with cilostamide (a phosphodiesterase-3 inhibitor) and the impact of...
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The impact of COVID-19 on human reproduction and directions for fertility treatment during the pandemic

Lee D

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly, resulting in a pandemic. The virus enters host cells through angiotensin-converting enzyme 2 (ACE2) and transmembrane protease...
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Update on genetic screening and treatment for infertile men with genetic disorders in the era of assisted reproductive technology

Lee SR, Lee TH, Song SH, Kim DS, Choi KH, Lee JH, Kim DK

A genetic etiology of male infertility is identified in fewer than 25% of infertile men, while 30% of infertile men lack a clear etiology, resulting in a diagnosis of idiopathic...
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Anorexigenic peptide (leptin, obestatin, nesfatin-1) levels and their impact on assisted reproductive technology treatment outcomes in patients with polycystic ovary syndrome

Varlı B, Şükür YE, Özmen B, Ergüder Bİ, Sönmezer M, Berker B, Atabekoğlu C, Aytaç R

Objective: In this study we aimed to assess anorexigenic peptide levels in patients with or without polycystic ovary syndrome (PCOS) and their effects on assisted reproductive treatment (ART) outcomes. Methods:...
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Glucocorticoid therapy in assisted reproduction

Kim YJ

As glucocorticoids are well-known as important regulators of stress and the immune system, their function and clinical use have elicited substantial interest in the field of reproduction. In particular, the...
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The antioxidant roles of L-carnitine and N-acetyl cysteine against oxidative stress on human sperm functional parameters during vitrification

Ghorbani F, Nasiri Z, Koohestanidehaghi Y, Lorian K

Objective: Amino acids can protect sperm structure in cryopreservation due to their antioxidant properties. Therefore, the present study aimed to investigate the protective effect of L-carnitine (LC) and N-acetyl cysteine...
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Progress in human ovarian rejuvenation: Current platelet-rich plasma and condensed cytokine research activity by scope and international origin

Sills ES, Wood SH

Objective: As clinicians and patients await consensus on intraovarian platelet-rich plasma (PRP) treatment, this project evaluated contemporary research trends in the literature. Methods: A PubMed/NLM search aggregated all ovarian PRP-related...
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Comparison of embryonic competence and clinical outcomes between early and late cumulus cell removal for in vitro fertilization

Pongsuthirak P

Objective: The impact of early mechanical removal of cumulus cells on fertilization and embryonic development is not yet precisely known. This study aimed to investigate the effects of early and...
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Delayed postpartum regression of theca lutein cysts with maternal virilization: A case report

Kim S, Lee I, Park E, Rhee YJ, Kim K, Aljassim AI, Park JH, Lee JH, Yun BH, Seo SK, Cho S, Choi YS, Lee BS

Theca lutein cysts are rare, benign lesions responsible for gross cystic enlargement of both ovaries during pregnancy. This condition is also termed hyperreactio luteinalis. Elevated human chorionic gonadotropin (hCG) levels...
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Adipose tissue-derived mesenchymal stem cells reduce endometriosis cellular proliferation through their anti-inflammatory effects

Meligy FY, Elgamal DA, Abdelzaher LA, Khashbah MY, El-Mokhtar MA, Sayed AA, Refaiy AM, Othman ER

Objective: Endometriosis is a chronic debilitating inflammatory condition characterized by the presence of endometrial tissues outside the uterine cavity. Pelvic soreness and infertility are the usual association. Due to the...
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Administration of red ginseng regulates microRNA expression in a mouse model of endometriosis

Lee JH, Park JH, Won BH, Im W, Cho S

Objective: Red ginseng (RG) exerts anti-inflammatory, anti-proliferative, and immunomodulatory effects on endometriosis through the regulation of microRNA (miRNA) expression. It may also ameliorate endometriosis by affecting the expression of multiple...
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Association between the serum estrone-to-estradiol ratio and parameters related to glucose metabolism and insulin resistance in women with polycystic ovary syndrome

Kim N, Chun S

Objective: We aimed to evaluate associations between the ratio of serum estrone (E1) to estradiol (E2) and parameters related to serum glucose metabolism and insulin resistance in women with polycystic...
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Decorin: a multifunctional proteoglycan involved in oocyte maturation and trophoblast migration

Park BS, Lee J, Jun JH

Decorin (DCN) is a proteoglycan belonging to the small leucine-rich proteoglycan family. It is composed of a protein core containing leucine repeats with a glycosaminoglycan chain consisting of either chondroitin...
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Impact of vitamin D3 supplementation on the in vitro growth of mouse preantral follicles

Shim YJ, Hong YH, Lee J, Jee BC

Objective: We investigated the impact of vitamin D3 (VD3) supplementation during mouse preantral follicle culture in vitro and the mRNA expression of 25-hydroxylase (CYP2R1), 1-alpha-hydroxylase (CYP27B1), and vitamin D receptor...
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