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Nanotechnology in reproductive medicine: Opportunities for clinical translation

Shandilya R, Pathak N, Lohiya NK, Sharma RS, Mishra PK

In recent years, nanotechnology has revolutionized global healthcare and has been predicted to exert a remarkable effect on clinical medicine. In this context, the clinical use of nanomaterials for cancer...
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Reanalysis of discarded blastocysts for autosomal aneuploidy after sex selection in cleavage-stage embryos

Ebrahimian N, Montazeri F, Sadeghi MR, Kalantar SM, Gilany K, Khalili MA

Objective: The goal of the present study was to investigate the rate of chromosomal aneuploidies in surplus embryos after sex determination at the cleavage stage. Then, the same chromosomal aneuploidies...
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Sperm chromatin structure assay versus sperm chromatin dispersion kits: Technical repeatability and choice of assisted reproductive technology procedure

B VL, Stephen S, Devaraj R, Mithraprabhu S, Bertolla RP, Mahendran T

Objective: The sperm DNA fragmentation index (DFI) guides the clinician’s choice of an appropriate assisted reproductive technology (ART) procedure. The DFI can be determined using commercially available methodologies, including sperm...
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A spontaneous pregnancy and live birth in a woman with primary infertility following the excision of an ovarian adrenal rest tumor: A rare case

Uyanıkoglu H, Ozer G, Kahraman S

Adrenal rest tumors are a rare extra-adrenal complication of congenital adrenal hyperplasia (CAH) in women although they are more commonly found in the testes of male patients with CAH. An...
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Dual trigger in normally-responding assisted reproductive technology patients increases the number of top-quality embryos

Şükür YE, Ulubaşoğlu H, İlhan FC, Berker B, Sönmezer M, Atabekoğlu CS, Aytaç R, Özmen B

Objective: The feasibility of a gonadotropin-releasing hormone agonist (GnRHa) trigger in normal responders is still a matter of debate. The aim of this study was to compare the number of...
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Autophagy in the uterine vessel microenvironment: Balancing vasoactive factors

Lim HJ

Autophagy, which has the literal meaning of self-eating, is a cellular catabolic process executed by arrays of conserved proteins in eukaryotes. Autophagy is dynamically ongoing at a basal level, presumably...
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Effect of evaporation-induced osmotic changes in culture media in a dry-type incubator on clinical outcomes in in vitro fertilization-embryo transfer cycles

Chi HJ, Park JS, Yoo CS, Kwak SJ, Son HJ, Kim SG, Sim CH, Lee KH, Koo DB

Objective: This study investigated whether adding outer-well medium to inhibit osmotic changes in culture media in a dry-type incubator improved the clinical outcomes of in vitro fertilization-embryo transfer (IVF-ET) cycles....
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Fertility-sparing treatment in women with endometrial cancer

Won S, Kim MK, Seong SJ

Endometrial cancer (EC) in young women tends to be early-stage and low-grade; therefore, such cases have good prognoses. Fertility-sparing treatment with progestin is a potential alternative to definitive treatment (i.e.,...
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The impact of post-warming culture duration on clinical outcomes of vitrified-warmed single blastocyst transfer cycles

Hwang JY, Park JK, Kim TH, Eum JH, Song H, Kim JY, Park HM, Park CW, Lee WS, Lyu SW

Objective: The objective of the study was to compare the effects of long-term and short-term embryo culture to assess whether there is a correlation between culture duration and clinical outcomes....
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Effect of a dual trigger on oocyte maturation in young women with decreased ovarian reserve for the purpose of elective oocyte cryopreservation

Kim SJ, Kim TH, Park JK, Eum JH, Lee WS, Lyu SW

Objective: The aim of this study was to determine whether co-administration of a gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (hCG) for final oocyte maturation improved mature oocyte cryopreservation...
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Impact of imatinib or dasatinib coadministration on in vitro preantral follicle development and oocyte acquisition in cyclophosphamide-treated mice

Hong YH, Kim SJ, Kim SK, Lee SC, Jun JH, Jee BC, Kim SH

Objective: We investigated the impact of tyrosine kinase inhibitor (imatinib or dasatinib) coadministration with cyclophosphamide (Cp) on preantral follicle development in an in vitro mouse model. Methods: Seventy-three female BDF1 mice...
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