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Effects of maternal age on embryo quality and pregnancy outcomes using testicular sperm with intracytoplasmic sperm injection

Choi HW, Park YS, Lee SH, Lim CK, Seo JT, Yang KM

OBJECTIVE: The aim of this study was to evaluate the influence of maternal age on fertilization, embryo quality, and clinical pregnancy in patients undergoing intracytoplasmic sperm injection (ICSI) using testicular...
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Pretreatment of normal responders in fresh in vitro fertilization cycles: A comparison of transdermal estradiol and oral contraceptive pills

Pereira N, Petrini AC, Zhou ZN, Lekovich J, Kligman I, Rosenwaks

OBJECTIVE: The aim of this study was to investigate the impact of pretreatment with transdermal estradiol (Eâ‚‚) compared to oral contraceptive pills (OCPs) on controlled ovarian stimulation (COS) response in...
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Chronic endometritis and infertility

Park HJ, Kim YS, Yoon TK, Lee WS

Chronic endometritis (CE) is a condition involving the breakdown of the peaceful co-existence between microorganisms and the host immune system in the endometrium. A majority of CE cases produce no...
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Anti-Müllerian hormone as a predictor of polycystic ovary syndrome treated with clomiphene citrate

Hestiantoro A, Negoro YS, Afrita Y, Wiweko B, Sumapradja K, Natadisastra M

OBJECTIVE: This study aimed to determine the threshold of anti-Müllerian hormone (AMH) as predictor of follicular growth failure in polycystic ovary syndrome (PCOS) patients treated with clomiphene citrate (CC). METHODS: Fifty...
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Efficacy and safety of dienogest in patients with endometriosis: A single-center observational study over 12 months

Park SY, Kim SH, Chae HD, Kim CH, Kang BM

OBJECTIVE: To evaluate the efficacy and safety of dienogest treatment in patients who had received dienogest for 12 months or more to treat endometriosis. METHODS: We analyzed the clinical data of...
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Efficient isolation of sperm with high DNA integrity and stable chromatin packaging by a combination of density-gradient centrifugation and magnetic-activated cell sorting

Chi HJ, Kwak SJ, Kim SG, Kim YY, Park JY, Yoo CS, Park IH, Sun HG, Kim JW, Lee KH

OBJECTIVE: This study was carried out to investigate the correlations of the sperm DNA fragmentation index (DFI) with semen parameters and apoptosis, and to investigate the effects of density-gradient centrifugation...
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The efficacy of intrauterine instillation of granulocyte colony-stimulating factor in infertile women with a thin endometrium: A pilot study

Lee D, Jo JD, Kim SK, Jee BC, Kim SH

OBJECTIVE: The study aimed to investigate the efficacy of intrauterine instillation of granulocyte colony-stimulating factor (G-CSF) on the day of ovulation triggering or oocyte retrieval in infertile women with a...
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Does intrauterine injection of low-molecular-weight heparin improve the clinical pregnancy rate in intracytoplasmic sperm injection?

Kamel AM, El-Faissal Y, Aboulghar , Mansour R, Serour GI, Aboulghar

OBJECTIVE: Heparin can modulate proteins, and influence processes involved in implantation and trophoblastic development. This study aimed to assess the improvement of clinical pregnancy and implantation rates after local intrauterine...
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Efficacy of oxytocin antagonist infusion in improving in vitro fertilization outcomes on the day of embryo transfer: A meta-analysis

Kim SK, Han EJ, Kim SM, Lee JR, Jee BC, Suh CS, Kim SH

OBJECTIVE: Uterine contraction induced by the embryo transfer (ET) process has an adverse effect on embryo implantation. The aim of this study was to determine the effect of oxytocin antagonist...
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Glucose-6-phosphate dehydrogenase deficiency does not increase the susceptibility of sperm to oxidative stress induced by Hâ‚‚Oâ‚‚

Roshankhah S, Rostami-Far Z, Shaveisi-Zadeh F, Movafagh A, Bakhtiari , Shaveisi-Zadeh J

OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect. G6PD plays a key role in the pentose phosphate pathway, which is a major source of nicotinamide adenine...
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