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Management Dilemma in Olanzapine Induced Restlessness and Cramps in Legs

Kar SK, Singh A

No abstract available.
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Disulfiram Induced Psychosis

Mohapatra , Rath NR

Disulfiram is the commonly prescribed drug for the treatment of alcohol dependence. It's major metabolite (diethyldithiocarbamate) is an inhibitor of dopamine-betahydroxylase, an enzyme that catalyzes the metabolism of dopamine to...
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Mirtazapine Is Effective in Steroid Withdrawal Syndrome Related Depression: A Case Report

Khanra S, Das S

Steroid withdrawal syndrome (SWS) following steroid dependence is becoming a common clinical condition. It may be associated with body image disorder. Though selective serotonin reuptake inhibitors (SSRIs) are found to...
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Mania in Wolfram's Disease: From Bedside to Bench

Chatterjee SS, Mitra S, Pal SK

Wolfram syndrome is a relatively unexplored entity in clinical psychiatry. Historically, the discovery of a specific WFS1 gene had generated huge fanfare regarding specific genetic causations of psychiatric disorders. While...
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Reduction of Severity of Recurrent Psychotic Episode by Sustained Treatment with Aripiprazole in a Schizophrenic Patient with Dopamine Supersensitivity: A Case Report

Tadokoro S, Nonomura N, Kanahara N, Hashimoto , Iyo M

Dopamine supersensitivity psychosis (DSP) is a type of acute exacerbation of recurrent psychosis caused by long-term treatment with antipsychotics in schizophrenic patients. Although DSP is exceedingly troublesome for clinicians, effective...
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Increased Levels of C1q in the Prefrontal Cortex of Adult Offspring after Maternal Immune Activation: Prevention by 7,8-Dihydroxyflavone

Han M, Zhang JC, Hashimoto

OBJECTIVE: Prenatal infection is implicated in the etiology of schizophrenia. The objective of this paper is to study the role of complement protein C1q in the psychosis of adult offspring...
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Sleep Problems as Predictors in Attention-Deficit Hyperactivity Disorder: Causal Mechanisms, Consequences and Treatment

Um YH, Hong SC, Jeong JH

Attention-deficit hyperactivity disorder (ADHD) is notorious for its debilitating consequences and early age of onset. The need for early diagnosis and intervention has frequently been underscored. Previous studies have attempted...
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Evaluation of Malondialdehyde, Superoxide Dismutase and Catalase Activity in Fetal Cord Blood of Depressed Mothers

Camkurt MA, Fındıklı E, Bakacak M, Tolun FÄ, Karaaslan

OBJECTIVE: The umbilical cord consists of two arteries and one vein and it functions in the transport between the maternal and fetal circulation. Biochemical analysis of fetal cord blood (FCB)...
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Neuroleptic Malignant Syndrome Associated with Valproate in an Adolescent

Yıldırım V, Direk MC, Güneş S, Okuyaz C, Toros F

Neuroleptic malignant syndrome (NMS) is a life-threatening idiosyncratic reaction that usually occurs after the administration of antipsychotic drugs. Antidepressants, benzodiazepines, and antiepileptic drugs are also suggested to be associated with...
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The Serum Levels of Resistin and Its Relationship with Other Proinflammatory Cytokines in Patients with Alzheimer's Disease

Demirci S, Aynalı A, Demirci K, Demirci S, Arıdoğan BC

OBJECTIVE: The present study aims to analyze the levels of resistin, tumor necrosis factor alpha (TNF-α), interleukin (IL)-1β, IL-6, IL-18, and C-reactive protein (CRP) in patients with Alzheimer's disease (AD)...
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Evaluation of Oxidative Status in Patients Treated with Electroconvulsive Therapy

Åženyurt M, Aybek H, Herken H, Kaptanoglu B, Korkmaz A

OBJECTIVE: Electroconvulsive therapy (ECT) is used in the treatment of many psychiatric diseases and this therapy may be effective on antioxidant defence system. In this study, we aimed to evaluate...
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Mechanisms of Alzheimer's Disease Pathogenesis and Prevention: The Brain, Neural Pathology, N-methyl-D-aspartate Receptors, Tau Protein and Other Risk Factors

Kocahan S, DoÄŸan Z

The characteristic features of Alzheimer's disease (AD) are the appearance of extracellular amyloid-beta (Aβ) plaques and neurofibrillary tangles in the intracellular environment, neuronal death and the loss of synapses, all...
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Association of CDKN2B-AS1 rs1333049 with Brain Diseases: A Case-control Study and a Meta-analysis

Zhao J, Wu X, Nie S, Gao X, Sun J, Li K, Zhang T, Huang Y

OBJECTIVE: CDKN2B-AS1 polymorphisms were shown to associate with the risk of stroke in European. The goal of this study was to evaluate the contribution of CDKN2B-AS1 rs1333049 to the risk...
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Predicting Autism Spectrum Disorder Using Blood-based Gene Expression Signatures and Machine Learning

Oh DH, Kim IB, Kim SH, Ahn DH

OBJECTIVE: The aim of this study was to identify a transcriptomic signature that could be used to classify subjects with autism spectrum disorder (ASD) compared to controls on the basis...
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The Normalization of Brain ¹⁸F-fluorodeoxy-D-glucose Positron Emission Tomography Hypometabolism following Electroconvulsive Therapy in a 55-year-old Woman with Treatment-resistant Late Onset Depression: A Case Report

Bak J, Lee SM, Kwon YJ, Shim SH, Kim JI

Major depressive disorder, especially in later life, has heterogeneous clinical characteristics and treatment responses. Symptomatically, psychomotor retardation, lack of energy, and apathy tends to be more common in people with...
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Teratogenicity of Antiepileptic Drugs

Güveli BT, Rosti RÃ, GüzeltaÅŸ A, Tuna EB, Ataklı D, Sencer S, Yekeler E, Kayserili , Dirican A, Bebek N, Baykan B, GökyiÄŸit A, Gürses C

OBJECTIVE: Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is...
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Measurement-based Treatment of Residual Symptoms Using Clinically Useful Depression Outcome Scale: Korean Validation Study

Jeon SW, Han C, Ko YH, Yoon SY, Pae CU, Choi J, Park YC, Kim JW, Yoon HK, Ko SD, Patkar AA, Zimmerman

OBJECTIVE: This study was aimed at evaluating the diagnostic validity of the Korean version of the Clinically Useful Depression Outcome Scale (CUDOS) with varying follow-up in a typical clinical setting...
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