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Combination of Nitrous Oxide with Isoflurane or Scopolamine for Treatment-resistant Major Depression

Yang C, Hashimoto

No abstract available.
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Olanzapine-induced Orthostatic Hypotension

Jana AK, Praharaj S, Roy N

Olanzapine is an atypical antipsychotic which is efficacious in the treatment of schizophrenia. The adverse effect profile for olanzapine is benign except for higher rates of metabolic events. Orthostatic hypotension...
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N-Acetyl Cysteine in the Treatment of Obsessive Compulsive and Related Disorders: A Systematic Review

Oliver G, Dean O, Camfield D, Blair-West S, Ng C, Berk M, Sarris J

OBJECTIVE: Obsessive compulsive and related disorders are a collection of debilitating psychiatric disorders in which the role of glutamate dysfunction in the underpinning neurobiology is becoming well established. N-acetyl cysteine...
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An Open Study of Sulforaphane-rich Broccoli Sprout Extract in Patients with Schizophrenia

Shiina A, Kanahara N, Sasaki T, Oda Y, Hashimoto , Hasegawa T, Yoshida T, Iyo M, Hashimoto

OBJECTIVE: Schizophrenia is a mental disorder characterized by severe cognitive impairment. Accumulating evidence suggests a role for oxidative stress in the pathophysiology of schizophrenia. Sulforaphane (SFN) extracted from broccoli sprout...
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Effects of Persisting Emotional Impact from Child Abuse and Norepinephrine Transporter Genetic Variation on Antidepressant Efficacy in Major Depression: A Pilot Study

Singh AB, Bousman CA, Ng CH, Byron K, Berk M

OBJECTIVE: Previous studies suggest child abuse and serotonergic polymorphism influence depression susceptibility and anti-depressant efficacy. Polymorphisms of the norepinephrine transporter (NET) may also be involved. Research in the area is...
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Tobacco Use in Bipolar Disorder

Thomson D, Berk M, Dodd S, Rapado-Castro M, Quirk SE, Ellegaard , Berk L, Dean OM

Tobacco use in mental health in general and bipolar disorder in particular remains disproportionally common, despite declining smoking rates in the community. Furthermore, interactions between tobacco use and mental health...
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Effect of Scopolamine Butylbromide on Clozapine-induced Hypersalivation in Schizophrenic Patients: A Case Series

Takeuchi I, Suzuki T, Kishi T, Kanamori D, Hanya M, Uno J, Fujita K, Kamei H

Clozapine has been demonstrated to be useful for treating refractory schizophrenia. However, hypersalivation occurs in 31.0-97.4% of the patients treated with clozapine. Accordingly, some patients who are disturbed by their...
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Dystonia in an Adolescent on Risperidone Following the Discontinuation of Methylphenidate: A Case Report

Guler G, Yildirim V, Kutuk MO, Toros F

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with common comorbidities that include oppositional defiant disorder, conduct disorder, anxiety disorder, and affective disorders. Because of these comorbidities, drug combination treatments and...
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Understanding Schizophrenia as a Disorder of Consciousness: Biological Correlates and Translational Implications from Quantum Theory Perspectives

Venkatasubramanian G

From neurophenomenological perspectives, schizophrenia has been conceptualized as "a disorder with heterogeneous manifestations that can be integrally understood to involve fundamental perturbations in consciousness". While these theoretical constructs based on...
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Pharmacotherapy of Bipolar Disorder with Quetiapine: A Recent Literature Review and an Update

Muneer A

Bipolar disorder is a chronic, recurrent condition with the usual onset during adolescence or early adulthood. In the Diagnostic and Statistical Manual of Mental Disorders 5th edition, it is conceptualized...
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Effect of Polymorphisms of Three Genes Mediating Monoamine Signalling on Brain Morphometry in Schizophrenia and Healthy Subjects

Vijayakumari AA, John JP, Halahalli , Paul P, Thirunavukkarasu P, Purushottam M, Jain S

OBJECTIVE: We examined the effect of risk alleles of polymorphisms of three schizophrenia risk genes that mediate monoamine signalling in the brain on regional brain volumes of schizophrenia and healthy...
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Shared and Distinct Neurocognitive Endophenotypes of Schizophrenia and Psychotic Bipolar Disorder

Kim D, Kim J, Koo T, Yun H, Won S

OBJECTIVE: Schizophrenia and bipolar disorder are characterized by the presence of neurocognitive impairments on the psychosis continuum. The present study aimed to explore the shared and distinct endophenotypes between these...
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The Influence of Levetiracetam in Cognitive Performance in Healthy Individuals: Neuropsychological, Behavioral and Electrophysiological Approach

Magalhaes , Gongora M, Vicente R, Bittencourt J, Tanaka G, Velasques , Teixeira S, Morato G, Basile LF, Arias-Carrion O, Pompeu FA, Cagy M, Ribeiro P

OBJECTIVE: The present study sought to analyze the influence of Levetiracetam (LEV) in cognitive performance by identifying the changes produced by LEV in reaction time, in neuropsychological assessment of attention...
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The Relationship between Cognitive Decline and Psychopathology in Patients with Schizophrenia and Bipolar Disorder

Kim MD, Seo HJ, Yun H, Jung YE, Park JH, Lee CI, Moon JH, Hong SC, Yoon BH, Bahk WM

OBJECTIVE: The primary goals of the present study were to assess intellectual function in participants with schizophrenia or bipolar disorder (BD) and to investigate the relationships between cognitive decline and...
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Dimensions of Delusions in Major Depression: Socio-demographic and Clinical Correlates in an Unipolar-Bipolar Sample

Zaninotto , Souery D, Calati R, Camardese , Janiri L, Montgomery S, Kasper S, Zohar J, De Ronchi , Mendlewicz J, Serretti A

OBJECTIVE: The present study aims at exploring associations between a continuous measure of distorted thought contents and a set of demographic and clinical features in a sample of unipolar/bipolar depressed...
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