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Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report

Kim YJ, No SH, Lee SY

  • KMID: 2171152
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):168-169.
Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only...
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Blonanserin-induced Mood Alteration in Schizophrenia and Schizoaffective Disorder: Two Cases

Min A, Kim D

  • KMID: 2171151
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):165-167.
We report two outpatients, one with schizophrenia and one with schizoaffective disorder, who developed manic or hypomanic episodes following the initiation of blonanserin during the course of treatment. Blonanserin is...
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The Neuroimmunology of Schizophrenia

Smyth AM, Lawrie SM

  • KMID: 2171143
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):107-117.
Schizophrenia (SCZ) is a polygenic, multi-factorial disorder and a definitive understanding of its pathophysiology has been lacking since it was first described more than a century ago. The predominant pharmacological...
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Transcranial Direct Current Stimulation in Schizophrenia

Agarwal SM, Shivakumar V, Bose A, Subramaniam A, Nawani H, Chhabra H, Kalmady SV, Narayanaswamy JC, Venkatasubramanian G

  • KMID: 2171144
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):118-125.
Transcranial direct current stimulation (tDCS) is an upcoming treatment modality for patients with schizophrenia. A series of recent observations have demonstrated improvement in clinical status of schizophrenia patients with tDCS....
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Effects of Color Temperature and Brightness on Electroencephalogram Alpha Activity in a Polychromatic Light-emitting Diode

Park JY, Ha RY, Ryu V, Kim E, Jung YC

  • KMID: 2171145
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):126-131.
OBJECTIVE: It has been reported that working and learning efficiency might be increased through artificially controlling the color temperature and brightness of light. However, the neurological bases of these outcomes...
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Comparative Study of Heart Rate Variability in Patients with Schizophrenia, Bipolar Disorder, Post-traumatic Stress Disorder, or Major Depressive Disorder

Moon E, Lee SH, Kim DH, Hwang B

  • KMID: 2171147
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):137-143.
OBJECTIVE: Heart rate variability (HRV) changes as a function of psychiatric illness. This study aimed to evaluate HRV among patients with various psychiatric disorders. METHODS: The present study recruited patients with...
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The Influence of Previous Antipsychotic Polypharmacy Versus Monotherapy on the Effectiveness of Antipsychotic after Switching to Paliperidone Extended-release

Lee HW, Na KS, Jung SH, Kang MH, Lee JS, Bae JN, Kim HY, Kim CE

  • KMID: 2171149
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):152-157.
OBJECTIVE: Although antipsychotic polypharmacy is widely used in the pharmacotherapy of schizophrenia, its effectiveness is controversial. In particular, clinicians tend to avoid switching to monotherapy in patients who have been...
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Long-term Efficacy and Tolerability of Perospirone for Young Help-seeking People at Clinical High Risk: a Preliminary Open Trial

Tsujino N, Nemoto T, Morita K, Katagiri N, Ito S, Mizuno M

  • KMID: 2171146
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):132-136.
OBJECTIVE: Interest in the "at-risk mental state" (ARMS) for psychosis has increased because early intervention is expected to delay or prevent the onset of schizophrenia. However, the optimum intervention strategy...
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Simultaneous Screening of 177 Drugs of Abuse in Urine Using Ultra-performance Liquid Chromatography with Tandem Mass Spectrometry in Drug-intoxicated Patients

Lee YW

  • KMID: 2171150
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):158-164.
OBJECTIVE: The demand for rapid and broad clinical toxicology screening methods to identify drugs of abuse and medicinal drugs is increasing steadily. Liquid chromatography-tandem mass spectrometry (LC-TMS) is increasingly used...
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Effects of Antipsychotics on the Inflammatory Response System of Patients with Schizophrenia in Peripheral Blood Mononuclear Cell Cultures

Al-Amin MM, Nasir Uddin MM, Mahmud Reza H

  • KMID: 2171148
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):144-151.
OBJECTIVE: We investigated the effects of antipsychotics on immune-challenged peripheral blood mononuclear cell (PBMC) cultures. METHODS: Blood samples were collected from twelve patients with first-episode schizophrenia. The PBMCs were separated and...
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