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A Case of Von Hippel-Lindau Disease Presented with Multiple Pancreatic Cysts and Medullary Hemangioblastoma

Kim YH, Jung HL, Yang A, Kwak JH, Kim DS, Shim JY, Shim JW

Von Hippel-Lindau (VHL) disease is a rare inherited cancer predisposition syndrome characterized by benign and malignant tumors in multiple organs, especially cerebellar hemangioblastomas, retinal angiomas, renal-cell carcinoma, and pheochromocytomas. Clinically,...
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Primary Extragonadal Germ Cell Tumors in Klinefelter Syndrome: 10-Years of Experience from a Single Institute

Kim Y, Ahn WK, Han JW, Hahn SM, Kwon SY, Lyu CJ

Background: Approximately 8% of male patients presenting with primary mediastinal germ cell tumors (GCTs) have Klinefelter syndrome (KS), while patients diagnosed with retroperitoneal GCTs also exhibit a range of chromosomal...
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Pediatric Palliative Care

Kim MS

In modern medical environment, death rates of newborn babies, children, and adolescents have decreased while the survival rate of life-threatening diseases has increased drastically. The relative 5 year survival rates...
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Management of Hepatoblastoma in the Modern Era and Future Perspectives

Suh JK, Kang S, Kim H, Koh KN, Im HJ

Hepatoblastoma is the most common malignant hepatic tumor in infants and young children and accounts for approximately 1% of all pediatric malignancies. A treatment strategy incorporating chemotherapy and surgical resection...
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A Recent Update on Histiocytic Disorder in Children: Focus on Diagnosis and Treatment

Yoon HS

The histiocytosis is rare disorder characterized by the accumulation of macrophages, dendritic cells, or monocyte-derived cells in various tissues and organs of children and adults. Classifying histiocytic disorders is difficult...
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Immunotherapy in Pediatric Solid Tumors

Choi JY

The survival rates for pediatric patients with solid tumors have improved dramatically in recent decades. However, patients with metastatic disease at diagnosis or progressive solid tumors still have a poor...
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Immunotherapy in Pediatric Hematologic Malignant Neoplasms

Hong KT

Childhood acute leukemia has achieved tremendous treatment outcome improvement over the past several decades. Given that pediatric leukemia remains the most common type of childhood malignant tumors, there are still...
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Current Knowledge on Inherited Platelet Function Disorders

Jung N, Shim YJ

Inherited platelet function disorders (IPFDs) are rare and underdiagnosed in individuals with clinically significant bleeding diathesis. IPFDs are classified according to the causative molecular defects involved in the process of...
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