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Arterial hypertension in Leigh syndrome due to m.13513G > A is multicausal, requiring an extensive search to identify its pathphysiology

Finsterer J

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Fok I and Bsm I gene polymorphism of vitamin D receptor and essential hypertension: a mechanistic link

Awasthi R, Manger P, Khare R

The vitamin D receptor (VDR) gene serves as a good candidate gene for susceptibility to essential hypertension. The gene regulates the renin angiotensin system by influencing blood pressure regulation. Around...
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Challenges of managing hypertension in Pakistan - a review

Elahi A, Ali A, Khan A, Samad Z, Shahab H, Aziz N, Almas A

Background This review aims to describe existing evidence on the state of hypertension in Pakistan, including the prevalence, associated risk factors, preventive strategies, and challenges in the management of hypertension. Methods A comprehensive...
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The association between carbon and nitrogen stable isotope ratios of human hair and hypertension

Ahn S, Park J

Background: The relationship between stable isotope ratios and dietary protein sources has been reported. How‑ ever, few studies have examined the effect of stable isotope ratios on metabolic risk in...
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Association between D-dimer and long-term mortality in patients with acute severe hypertension visiting the emergency department

Kim B, Shin J

Objective High levels of D-dimer, a marker of thrombotic events, are associated with poor outcomes in patients with various cardiovascular diseases. However, there has been no research on its prognostic implications...
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Coffee intake and hypertension in Korean adults: results from KNHANES 2012–2016

Shah S, Cho IJ, Lee W, Pyun WB, Ha E

Background Coffee is the most popular and widely consumed drink in the world. Coffee consumption seems to have both benefits and risk with respect to hypertension; results from studies evaluating effect...
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Korea hypertension fact sheet 2022: analysis of nationwide population-based data with a special focus on hypertension in the elderly

Kim HC, Lee H, Lee HH, Lee G, Kim E, Song M, Moon J, Seo Y, for the Korean Society of Hypertension (KSH)-Hypertension Epidemiology Research Working Group

Background The Korean Society of Hypertension has published the Korea Hypertension Fact Sheet 2022 to provide an overview of the magnitude and management status of hypertension and their recent trends. Methods The Fact...
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Arterial stiffness and hypertension

Kim H

Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and...
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Therapeutic roles of thiazides and loop diuretics in blood pressure control and renal protection against chronic kidney disease

Jo W, Koh ES, Chung S

Fluid overload secondary to loss of functional nephron mass can elevate blood pressure, which is characteristic of hypertension shown in chronic kidney disease (CKD). Therefore, it is logical to use...
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An evidence-based guide to the efficacy and safety of isometric resistance training in hypertension and clinical implications

Baffour‑Awuah B, Pearson M, Dieberg G, Wiles J, Smart N

More than 30 randomized controlled trials, supported by individual patient-level and group-level meta-analyses and a Delphi analysis of expert opinion, unequivocally show isometric resistance training (IRT) elicits antihypertensive benefits in...
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Case report: malignant hypertension associated with catecholamine excess in a patient with Leigh syndrome

Solis A, Shimony J, Shinawi M, Barton K

Background Leigh syndrome is a progressive neurodegenerative mitochondrial disorder caused by multiple genetic etiologies with multisystemic involvement that mostly affecting the central nervous system with high rate of premature mortality. Case presentation We...
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Role of home blood pressure monitoring in resistant hypertension

Kim HM, Shin J

The definition of resistant hypertension (RHT) has been updated to include failure to achieve target blood pressure (BP) despite treatment with ≥3 antihypertensive drugs, including diuretics, renin-angiotensin system blockers, and...
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Relationship between the methylenetetrahydrofolate reductase (MTHFR) rs1801133 SNP and serum homocysteine levels of Zhuang hypertensive patients in the central region of Guangxi

Hu XJ, Su MR, Cao BW, Ou FB, Yin RX, Luo AD

Background The relationship between the methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphism (SNP) and serum homocysteine (Hcy) levels or H-type hypertension in different populations is inconsistent. This study aimed to explore the...
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Prevalence of hypertension among antiretroviral therapy naïve patients in Lagos, Nigeria

Odubela O, Odunukwe N, Peer N, Musa A, Salako B, Kengne A

Background The gains from successful antiretroviral therapy (ART) roll-out could be compromised by the increasing burden of non-communicable diseases, particularly cardiovascular diseases among people living with HIV (PLWH). Hypertension remains a...
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Diagnosis and treatment of hypertension in dialysis patients: a systematic review

Kim IS, Kim S, Yoo TH, Kim JK

In patients with end-stage renal disease (ESRD) undergoing dialysis, hypertension is common but often inadequately controlled. The prevalence of hypertension varies widely among studies because of differences in the definition...
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Suboptimal control status of young hypertensive population

Shin D, Choi J, Lee H

The prevalence of hypertension (HT) among young adults aged 18 to 39 years is estimated to be 3.7% to 8.6% worldwide. Although the prevalence of HT in young adults is...
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Resistant hypertension: consensus document from the Korean society of hypertension

Park S, Shin J, Ihm S, Kim K, Kim H, Kim H, Lee E, Lee J, Ahn S, Cho E, Kim J, Kang H, Lee H, Lee S, Kim W, Park J

Although reports vary, the prevalence of true resistant hypertension and apparent treatment-resistant hypertension (aTRH) has been reported to be 10.3% and 14.7%, respectively. As there is a rapid increase in...
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Exercise-induced desaturation during a six-minute walk test is associated with poor clinical outcomes in patients with pulmonary arterial hypertension

Choi J, Shin M, Lee B, Park J

Background The six-minute walk test (6MWT) is an established exercise test for patients with pulmonary arterial hypertension (PAH), affording insight into both exercise intolerance and overall prognosis. Despite the widespread application...
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Statement on chronotherapy for the treatment of hypertension: consensus document from the Korean society of hypertension

Park S, Ihm SH, Cho IJ, Kim DH, Park JH, Chung WB, Choi S, Lee HY, Kim HC, Sohn IS, Lee EM, Kim JH, Kim Ki, Cho EJ, Sung KC, Shin J, Pyun WB

Nocturnal blood pressure (BP) has been shown to have a significant predictive value for cardiovascular disease. In some cases, it has a superior predictive value for future cardiovascular outcomes than...
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The 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension

Kim H, Lee E, Ahn S, Kim K, Kim H, Kim J, Lee H, Lee J, Park J, Cho E, Park S, Shin J, Kim Y

Hypertension is the leading cause of death in human being, which shows high prevalence and associated complica‑ tions that increase the mortality and morbidity. Controlling blood pressure (BP) is very...
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