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Effect of Troglitazone on Glycogen synthase Activity in Human skeletal Muscle Culture from Obese Non-Diabetic and Obese Non-insulin Dependent Diabetes Mellitus

Carter LA, Ciaraldi T, Henry RR, Park KS, Lee HK

  • KMID: 2137370
  • J Korean Diabetes Assoc.
  • 1997 Sep;21(3):254-261.
BACKGROUND: Skeletal muscle is the principal tissue of insulin resistance in obese and non-insulin dependent diabetic(NIDDM) subjects. Troglitazone, a member of thiazolidinedione class of compounds, has been shown to improve...
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Effects of lovastatin on free fatty acid oxidation in human skeletal muscle cells

Kim DL, Song KH, Kim SK, Kim HR, Ciaraldi T, Henry RR

  • KMID: 2081277
  • Korean J Med.
  • 2007 Jun;72(6):600-606.
BACKGROUDN: Recent clinical studies have suggested that statins improve insulin resistance and glucose metabolism in the skeletal muscle of diabetic patients. To evaluate a possible component of this action, we...
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Metabolic Phenotype of Glycogen Synthase Gene Inhibition in Human Skeletal Muscle Cells

Koh JJ, Park KS, Kim JM, Kim SY, Lee HK, Ciaraldi T, Henry RR

  • KMID: 1539950
  • J Korean Diabetes Assoc.
  • 2000 Jun;24(3):331-339.
BACKGROUND: Glycogen synthase (GS) is the rate-limiting enzyme controlling non-oxidative glucose disposal in skeletal muscle. Reduction in GS activity and impaired insulin responsiveness are characteristic features of skeletal muscle in...
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Effect of Troglitazone on Glucose Transport in Human Skeletal Muscle Cell Cultures from Obese Non-diabetic and Obese Non-insulin Dependent Diabetes Mellitus

Ciaraldi T, Henry RR, Park KS, Lee HK

  • KMID: 2178010
  • J Korean Diabetes Assoc.
  • 1998 Jun;22(2):164-172.
BACKGROUND: Skeletal muscle is the principal tissue of insulin resistance in obese non-diabetic and non-insulin dependent diabetic(NIDDM) subjects. Troglitazone(Tgz), a member of thiazolidinedione class of compounds, has been shown to...
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