- Paraplegia following Chemonucleolysis A Case Report and Discussion of Neurotoxicity
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Chang DI, Kim JH, Kim MH
- KMID: 1661994
- J Korean Neurol Assoc.
- 1986 Dec;4(2):231-234.
Chymopapain was discovered by Jensen in 1941, and in 1963 Smith demonstrated the chondrolytic properties of chymopapain. Since then, many patients have been injected with this agent. Although there are... -
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- The Experimental Study on Central & Peripheral Nerve Tissue Responses to the Chymopapain in Rabbits
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Wang JM
- KMID: 1965804
- Ewha Med J.
- 1989 Dec;12(4):319-327.
- doi: 10.12771/emj.1989.12.4.319
The treatment of herniated lumbar disc has been a challenging problem in spite of various methods of treatments such as conservative, chymopapain injection, percutaneous automated nucleotome method and surgical removeal... -
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- Discographic Findings in the Lumbar Disc Herniations
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Kim YS, Kim SJ
- KMID: 1953125
- J Korean Neurosurg Soc.
- 1988 Dec;17(6):1397-1406.
The authors analysed the findings of discograms in the 1355 levels of 900 herniated lumbar disc cases during May 1984 to January 1987. Prior to intradiscal injection of Chymopapain in... -
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- Therapeutic Results of Chemonucleolysis in Patients with Herniated Lumbar Discs
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Park KH, Choi JS, Park WY, Kang CG, Kim DH, Kim DJ
- KMID: 2339496
- J Korean Neurosurg Soc.
- 1986 Dec;15(4):567-572.
We had experienced 60 cases of chemonucleolysis with Discase(R)(chymopapain for injection) under careful patient selection of herniated lumbar discs and had followed up thereafter at least 3 months since July,... -
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- CT Scan and Discographic Findings in Ruptured Lumbar Discs
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Kim YS, Park YG
- KMID: 2138533
- J Korean Neurosurg Soc.
- 1985 Jun;14(2):377-388.
The herniated lumbar intervertebral disc, a common affliction in man, had been diagnosed with myelogram and treated with laminectomy. Recently, the application of CT scan and chemonucleolysis markedly changed the... -
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- The Relationship of the Discographic Finding to the Chemonucleolysis Results
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Kim YS, Kim SJ
- KMID: 1953129
- J Korean Neurosurg Soc.
- 1988 Dec;17(6):1433-1440.
The authors analysed the relationship of the discographic finding to the chemonucleolysis results of herniated lumbar disc during May 1984 to January 1987. Among 900 herniated lumbar disc cases, 882... -
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- Effects of Vasoactive Drugs on Blood Flow in Rabbits: Photoplethysmographic Assessment
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Chung MS, Lo M, Chung MY, Lee HK, Lee SH
- KMID: 2445566
- J Korean Orthop Assoc.
- 1987 Dec;22(6):1397-1415.
- doi: 10.4055/jkoa.1987.22.6.1397
The dynamic blood flow is regulated by the numerous complex mechanisms. Since blood flow varies directly with the radius of the vessel, blood flow is markedly affected by small changes... -
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- Lumbar disc ultrasonography for evaluation of chemonucleolysis : A preliminary report
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Chung TS, Kim YS, Park HC, Suh JH, Kim DI, Oh SH
- KMID: 2359259
- J Korean Radiol Soc.
- 1988 Jun;24(3):358-367.
- doi: 10.3348/jkrs.1988.24.3.358
There has been no reported change of ultrasonographic findings of nucleus pulposus on chemonucleolysis. Wehave found that the particles of herniated nudeus pulposus are highly echogenic and change to low... -
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- The Discolytic Effects of Disken(R)(Chymopapain, made in Korea): Experimental Study
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Kim JM, Kim KM, Chung HY, Kim NK, Oh SJ, Lee JD
- KMID: 1953108
- J Korean Neurosurg Soc.
- 1988 Dec;17(6):1237-1248.
The purpose of this study is to evaluate the effect of Disken(R)(chymopapain) on the intervertebral discs of Mongolian Dogs. Three healthy Mongolian dogs at same age(9 months) were underwent laparotomy,... -
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- Chymopapain chemonucleolysis : CT changes after treatment
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Lee MJ, Lee KY, Lee SH, Lee CJ
- KMID: 2359286
- J Korean Radiol Soc.
- 1988 Apr;24(2):233-244.
- doi: 10.3348/jkrs.1988.24.2.233
The herniated nucleus pulposus(HNP) is a very common disorder. In those patient, who do not respond, moredirect therapeutic measures, may be necessary. The chymopapain cheomonuclelysis, after two decades of development,has... -
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- A Clinical Study of Chemonucleolysis for Herniated Lumbar Discs
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Park KW, Kim SY
- KMID: 2339497
- J Korean Neurosurg Soc.
- 1986 Dec;15(4):573-586.
The authors analysed 522 patients treated with chymopapain for herniated lumbar discs from May 1984 to December 1985 at the Dept. Neurosurgery, Yongdong Severance Hospital, Yonsei University College of Medicine.... -
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- A Clinical Study of Cervical Chemonucleolysis
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Jeon BC, Seo SW
- KMID: 2187992
- J Korean Neurosurg Soc.
- 1996 May;25(5):984-991.
For many years chemonucleolysis has been proven effective in the curative treatment of lumbar disc herniation. However, this technique is seldom popular in the herniated cervical disc. For several years... -
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- Clinical Results of Chemonucleolysis for the Far Lateral Lumbar Disc Herniation
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Jin BH, Kim YS, Yoon DH, Cho YE
- KMID: 2067585
- J Korean Neurosurg Soc.
- 1999 May;28(5):675-682.
The far lateral lumbar disc herniation occurs ten times less often than the classic posterolateral disc herniations. Its clinical presentation, the anatomy involved, and difficulty of surgical treatment are not... -
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- The Clinical Study of Chemonucleolys in Herniated Nucleus Pulposus of Lumbar Spine
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Shin HS, Lee SK, Kim SJ, Kim BJ
- KMID: 1954485
- J Korean Neurosurg Soc.
- 1991 Nov;20(10-11):868-874.
Chemonucleolysis with chymopapain has been shown to be an effective alternative to surgery for the treatment of Sciatica secondary to lumbar disc herniation after failure of conservative treatment. 92 lumbar... -
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- Hereditary Ovarian Cancer: Report of 6 Families
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Kang SB, Kweong JH, Koh CW, Song YS, Lee HP, Park JG
- KMID: 1675661
- Korean J Gynecol Oncol Colposc.
- 1995 Sep;6(3):204-213.
Hereditary ovarian cancer accounts for about 5% to 10% of the total ovarian cancer bnurden, The discase has been observed in context with three types of hereditary ovarian cancer prone... -
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- Ozone Chemonucleolysis on the Lumbar Intervertebral Disc of the Rabbit
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Kim YS, Jeon BC, Kwon KY
- KMID: 2339778
- J Korean Neurosurg Soc.
- 2003 Dec;34(6):570-574.
OBJECTIVE: This study is aimed to evaluate the chemonucleolytic effect of medical ozone by investigating the change of the signal intensity on magnetic resonance imaging (MRI) scan after injection of... -
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- Retrospective Outcome Evaluation of Cervical Chemonucleolysis with Digital Infrared Thermographic Imaging
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Kim TY, Jeon BC, Lee HD, Seo SW
- KMID: 1955454
- J Korean Neurosurg Soc.
- 1999 Jan;28(1):48-54.
The diagnostic efficacy and comparability of digital infrared thermographic imaging(DITI), computerized tomographic(CT) scan and magnetic resonance imaging(MRI) in the assessment of outcome of chemonucleolysis for herniated soft cervical disc patients... -
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- Chemonucleolysis using Chondroitinase ABC: An Expreimental Study
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Ahn JI, Park JS, Oh DI
- KMID: 2423182
- J Korean Orthop Assoc.
- 1994 Aug;29(4):1120-1128.
- doi: 10.4055/jkoa.1994.29.4.1120
Chymopapain and collagenase are well known chemonucleolytic agents for lumbar disc herniation. However, these enzymes have serious problems occasionally, such as severe neurotoxicity or anaphylaxis even fatal to patients. Chondroitinase... -
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- Evoked Potential Studies in the Primary Cerebellar Ataxias
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Kim JS, Lee KW, Myung HJ
- KMID: 1957554
- J Korean Neurol Assoc.
- 1987 Dec;5(2):159-165.
Visual (VEP), brainstem auditory (BAEP), and median nerve somatosensory (MNSEP) evoked potentials were studied in 18 patients with primary cerebellar ataxia, and were found to be abnormal in 30%, 17%,... -
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- Lumbar CT Findings and Results of Chemonucleolysis
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Oh SH, Kim YS
- KMID: 2339537
- J Korean Neurosurg Soc.
- 1988 Oct;17(5):943-954.
The therapeutic response to treatment of lumbar disk heniation with chymopapain chemonucleolysis is significantly influenced by the criteria used for patient selection. In an attempt to identify objective pretreatment radiographic... -
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