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Death-associated Protein Kinase 1 Phosphorylates α-Synuclein at Ser129 and Exacerbates Rotenone-induced Toxic Aggregation of α-Synuclein in Dopaminergic SH-SY5Y Cells

Shin WH, Chung KC

  • KMID: 2503981
  • Exp Neurobiol.
  • 2020 Jun;29(3):207-218.
  • doi: 10.5607/en20014
The formation of Lewy bodies (LBs), intracellular filamentous inclusions, is one of the hallmarks of Parkinson's disease (PD). α-Synuclein is the main component of LBs and its abnormal accumulation contributes...
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New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome

Park J, Chung KC

Down syndrome (DS) is one of the most common genetic disorders accompanying with mental retardation, cognitive impairment, and deficits in learning and memory. The brains with DS also display many...
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Superior Rectus-Levator Palpebrae Complex Myositis Presenting as Isolated Painless Ptosis

Lee D, Heo SH, Lee JH, Kwon YN, Nam H, Lee J, Park KC, Ahn TB, Yoon SS, Chang DI, Chung KC

  • KMID: 2343512
  • J Korean Neurol Assoc.
  • 2013 Nov;31(4):286-288.
No abstract available.
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Prediction of Hemorrhagic Transformation and Functional Outcome Using HAT Score in Acute Ischemic Stroke Patients Treated with Intravenous Alteplase

Heo SH, Yi SH, Lee D, Hwang KJ, Jung YJ, Park KC, Ahn TB, Yoon SS, Chung KC, Chang DI

  • KMID: 1966505
  • J Korean Neurol Assoc.
  • 2012 May;30(2):110-115.
BACKGROUND: Intravenous thrombolysis with alteplase is the most effective therapy for acute ischemic stroke, but hemorrhagic transformation (HT) is a potentially dangerous complication of such thrombolysis. Few studies have investigated...
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Plaque Rupture is a Determinant of Vascular Events in Carotid Artery Atherosclerotic Disease: Involvement of Matrix Metalloproteinases 2 and 9

Heo SH, Cho CH, Kim HO, Jo YH, Yoon KS, Lee JH, Park JC, Park KC, Ahn TB, Chung KC, Yoon SS, Chang DI

BACKGROUND AND PURPOSE: Unstable carotid atherosclerotic plaques are characterized by cap rupture, leading to thromboembolism and stroke. Matrix metalloproteinases (MMPs) have been implicated in the progression of atherosclerosis and plaque...
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Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death

Choi HK, Chung KC

Dual-specificity tyrosine (Y)-phosphorylation-regulated protein kinase 1A (Dyrk1A) is the mammalian homologue of Drosophila melanogaster minibrain and its human gene is mapped to the Down syndrome critical region of chromosome 21....
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Association of Serum Uric Acid With Early Prognosis Stratified by the Stroke Subtype in Patients With Moderate to Severe Ischemic Stroke

Kim JH, Heo SH, Kim JH, Park KC, Ahn TB, Yoon SS, Chung KC, Chang DI

  • KMID: 2184973
  • J Korean Neurol Assoc.
  • 2010 Aug;28(3):149-156.
BACKGROUND: The role of uric acid in cerebrovascular disease is controversial. Uric acid may be an independent risk factor for cerebrovascular diseases but its neuroprotective role as an antioxidant has...
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Cerebral Infarction in a Young Female Patient With Renovascular Hypertension Caused by Fibromuscular Dysplasia

Lee DK, Heo SH, Kwon SH, Park KC, Ahn TB, Yoon SS, Chang DI, Chung KC

  • KMID: 2343387
  • J Korean Neurol Assoc.
  • 2010 Nov;28(4):326-328.
No abstract available.
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The Usefulness of Arthroscopy in the Operative Treatment of Intra-Articular Calcaneal Fracture

Chung KC, Gwak HC, Kim CW, Kim JH, Park DH

  • KMID: 2063750
  • J Korean Foot Ankle Soc.
  • 2009 Jun;13(1):55-59.
PURPOSE: We tried to evaluate the usefulness of the arthroscopy in the operative treatment of intra-articular calcaneal fracture. MATERIALS AND METHODS:Between March 2005 and May 2008, 9 patients with intra-articular calcaneal...
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Change of Serum Neuron Specific Enolase Level During Acute Stage of Cerebral Infarction

Ku BD, Chung KC

  • KMID: 2343349
  • J Korean Neurol Assoc.
  • 2009 Feb;27(1):13-18.
BACKGROUND: Neuron-specific enolase (NSE) is a useful indicator of neuronal injury in acute cerebral infarction. We investigated the changes in serial serum NSE levels in patients with acute cerebral infarction. METHODS:...
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Polyneuropathy and Cerebral Infarction Complicating Scrub Typhus

Kim JH, Lee SA, Ahn TB, Yoon SS, Park KC, Chang DI, Chung KC

We describe a 64-year-old man with scrub typhus who presented with both polyneuropathy and cerebral infarction. A eurological examination revealed a confused mental state, stiff neck, hearing impairment, symmetric weakness,...
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Migrainous Vertigo

Chung KC, Kim BK

Patients with migraine frequently have hypersensitivity to light, sound, and smell. In addition to these hallmark features of migraine, patients often describe vestibular complaints ranging from true vertigo to less...
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A Case of Occipital Condyle Syndrome Associated with Hepatocellular Carcinoma

Lee SB, Lee YH, Rhee HY, Yoon SS, Ahn TB, Chang DI, Chung KC, Park KC

  • KMID: 2343268
  • J Korean Neurol Assoc.
  • 2007 Aug;25(3):413-415.
Occipital condyle syndrome, which consists of unilateral occipital region pain associated with ipsilateral 12th cranial nerve paresis, is a rare, but stereotypic syndrome. Herein, we report a patient with occipital...
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A Case of Isolated Traumatic Caudate Lesion with Marked Improvement in Visuospatial Function by Donepezil

Kang MC, Yi SH, Ahn TB, Park KC, Yoon SS, Chang DI, Chung KC

  • KMID: 2343258
  • J Korean Neurol Assoc.
  • 2007 Aug;25(3):377-380.
Visuospatial dysfunction after isolated caudate lesion and improvement by donepezil has not been reported. Herein we report a 46-year old woman with visuospatial dysfunction after an isolated traumatic caudate lesion....
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Iliopsoas Bursitis following Total Hip Replacement Arthroplasty: A Case Report

Choi JS, Chung KC, Kim JH

PURPOSE: To report the clinical, radiological and surgical findings of iliopsoas bursitis, and to suggest an indication for diagnosis and treatment. MATERIALS AND METHODS: We report two patients with iliopsoas bursitis...
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Clinical Characteristics of Nonagenarian Stroke

Heo SH, Chang DI, Seo KH, Bu SH, Kang MC, Lee SB, Park KC, Ahn TB, Yoon SS, Chung KC

  • KMID: 1527856
  • J Korean Neurol Assoc.
  • 2007 May;25(2):137-142.
BACKGROUND: As the elderly population is fast growing, the incidence of stroke is also increasing. We studied the clinical characteristics of nonagenarian stroke compared to a population of patients under...
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A Case Suggesting Spontaneous Spinal Cord Herniation Presented as Brown-Sequard Syndrome

Heo SH, Kim JH, Ahn TB, Kim EJ, Park KC, Yoon SS, Chang DI, Chung KC

  • KMID: 2185273
  • J Korean Neurol Assoc.
  • 2007 Feb;25(1):133-135.
No abstract available.
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Amnesic Syndrome in a Mammillothalamic Tract Infarction

Park KC, Yoon SS, Chang DI, Chung KC, Ahn TB, Ku BD, Adair JC, Na DL

It is controversial whether isolated lesions of mammillothalamic tract (MTT) produce significant amnesia. Since the MTT is small and adjacent to several important structures for memory, amnesia associated with isolated...
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Assessment of Validity, Reliability and Responsiveness of Korean Knee Injury and Osteoarthritis Outcome Score(KOOS) for the Knee Injury

Seo SS, Chung KC, Kim YB

  • KMID: 2398703
  • J Korean Orthop Assoc.
  • 2006 Jun;41(3):441-453.
PURPOSE: To assess the suitability of the Korean KOOS (Knee injury and osteoarthritis outcome score) as a patient-centered clinical measurement of the validity, reliability and responsiveness to the treatment of...
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Expression Patterns of Tbx1 during Development of the Mouse Mandibular First Molar

Bok SM, Chung KC, Cho ES

  • KMID: 2224469
  • Korean J Anat.
  • 2006 Jun;39(3):187-195.
A T-box transcription factor gene, Tbx1 is a principal candidate of the most frequent chromosomal deletion syndrome found in human, DiGeorge/velocardiofacial syndrome which is a complex developmental disorder associated with cardiac outflow...
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