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Eosinophils Modulate CD4+ T Cell Responses via High Mobility Group Box-1 in the Pathogenesis of Asthma

Shim EJ, Chun E, Lee HS, Bang BR, Cho SH, Min KU, Park HW

Eosinophils have been reported to modulate T cell responses. Previously, we reported that high-mobility group box 1 protein (HMGB1) played a key role in the pathogenesis of asthma. This study...
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IL-13 and STAT6 signaling involve in low dose lipopolysaccharide induced murine model of asthma

Bang BR, Lee HS, Lee SY, Chun E, Kim YK, Cho SH, Min KU, Kim YY, Park HW

BACKGROUND: We reported that level of lipopolysaccharide (LPS) exposure determined the type of airway inflammation in a murine model of asthma. OBJECTIVE: The purpose of this study is to evaluated the...
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Alveolar macrophages modulate allergic inflammation in a murine model of asthma

Bang BR, Chun E, Shim EJ, Lee HS, Lee SY, Cho SH, Min KU, Kim YY, Park HW

The role of alveolar macrophages (AMs) in the pathogenesis of asthma is still unknown. The aim of the present study was to investigate the effects of AM in the murine...
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Expression of Semaphorin 3A and Neuropilin 1 in Asthma

Shim EJ, Chun E, Kang HR, Cho SH, Min KU, Park HW

Neuropilin 1 (NP1) is a part of essential receptor complexes mediating both semaphorin3A (SEMA3A) and vascular endothelial growth factor (VEGF) which is one of important mediators involved in the pathogenesis...
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Hepatitis B virus X Protein Promotes Liver Cancer Progression through Autophagy Induction in Response to TLR4 Stimulation

Son J, Kim MJ, Lee JS, Kim JY, Chun E, Lee KY

Hepatitis B virus X (HBx) protein has been reported as a key protein regulating the pathogenesis of HBV-induced hepatocellular carcinoma (HCC). Recent evidence has shown that HBx is implicated in...
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