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The burden of symptomatic patients with chronic spontaneous urticaria: a real-world study in Korea

Ye YM, Koh YI, Choi JH, Kim MA, Park JW, Kim TB, Nam YH, Chang YS, Park HS

Background/Aims: Chronic spontaneous urticaria (CSU) poses a considerable burden both on the quality of life (QoL) of individual patients and on healthcare systems. Real‑world data evaluating the disease burden of...
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Anxiety, depression, and stress in Korean patients with chronic urticaria

Choi GS, Nam YH, Park CS, Kim MY, Jo EJ, Park HK, Kim HK

Background/Aims: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to...
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The Relation of Autologous Serum Skin Test andAutologous Plasma Skin Test Result with VariousClinical and Laboratory Findings in Patients withChronic Spontaneous Urticaria

Park GH, Choi JH, Kim S, Bae Y

Background: Despite the autologous serum skin test (ASST)and autologous plasma skin test (APST) is widely used test accessingwhether a patient with chronic spontaneous urticaria(CSU) has autoreactivity or not, the clinician...
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Health-Related Utility of EQ-5D in Korean Adults With Chronic Urticaria: Mapping From Urticaria Outcome Measures

Lee MS, Yoon J, Kim J, Shin YS, Park HS, Lee HY, Ye YM

Purpose: A need for useful measures reflective of the socio-economic burden of chronic urticaria (CU) has arisen. To obtain utility estimates for CU, we investigated EuroQol-5-Dimension (EQ-5D) indices according to...
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Urticaria: Classification and Diagnosis

Ye YM

Urticaria is a common cutaneous disease characterized by recurrent and transient wheals and pruritus, sometimes accompanied angioedema. The classification of urticaria is based on the duration of the disease and...
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Emerging Therapies in Chronic Spontaneous Urticaria

Min TK, Saini SS

Chronic spontaneous urticaria (CSU) is characterized by typically short-lived and fleeting wheals, angioedema or both, which occur spontaneously and persist for longer than 6 weeks. This term is applied to...
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Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria

Ulambayar , Lee H, Yang EM, Park HS, Lee K, Ye YM

Translationally controlled tumor protein (TCTP) is also known as histamine releasing factor as it has the ability to activate mast cells. To investigate the role of TCTP in the pathogenesis...
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Drug eruption by antihistamine mistaken for chronic urticaria in a child

Lee GM, Chu SY, Kang SY, Kim HB, Park JS, Kim JK

Although rare, antihistamines can cause adverse effects, including drug-induced eruptions or anaphylaxis. A 4-year-old child visited the pediatric department of a hospital for skin eruptions after administration of antihistamines, (e.g.,...
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Adaptation and Validation of the Korean Version of the Urticaria Control Test and Its Correlation With Salivary Cortisone

Lee JH, Bae YJ, Lee SH, Kim SC, Lee HY, Ban GY, Shin YS, Park HS, Kratzsch J, Ye YM

PURPOSE: Frequent changes in chronic urticaria (CU) activity over time can cause psychological stress, which also serves as a trigger of CU. To measure the control status of CU, the...
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A Study on the Clinical Aspects of Chronic Urticaria in Children

Ryu HR, Kim JH, Choi WJ, Roh JY, Baek JO

  • KMID: 2401250
  • Korean J Dermatol.
  • 2017 Dec;55(10):641-650.
BACKGROUND: Although the incidence of chronic urticaria in children is increasing, research on the disease is limited. OBJECTIVE: We aimed to study the clinical and etiological characteristics of chronic urticaria in...
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Prevalence and Risk Factors of Urticaria With a Focus on Chronic Urticaria in Children

Lee SJ, Ha EK, Jee HM, Lee KS, Lee SW, Kim MA, Kim DH, Jung YH, Sheen YH, Sung MS, Han MY

PURPOSE: Limited data is available on the prevalence and risk factors of acute and chronic urticaria in children. Our purpose was to determine the prevalence and identify the risk factors...
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Prognostic Factors for Chronic Spontaneous Urticaria: A 6-Month Prospective Observational Study

Ye YM, Park JW, Kim SH, Ban GY, Kim JH, Shin YS, Lee HY, Park HS, PRANA Group

PURPOSE: Chronic urticaria (CU) has a substantial impact on the quality of life. Little clinical data on the prognosis of CU has been reported. This study aimed to investigate the...
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A stepwise approach in the management of chronic spontaneous urticaria in children

Lee XH, Ong LX, Cheong JY, Sultana R, Rao R, Lim HH, Ding XM, Loh WY, Punan M, Chiang WC

BACKGROUND: There is limited literature in the management of chronic urticaria in children. Treatment algorithms are generally extrapolated from adult studies. OBJECTIVE: Utility of a weight and age-based algorithm for antihistamines...
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Basophil Markers for Identification and Activation in the Indirect Basophil Activation Test by Flow Cytometry for Diagnosis of Autoimmune Urticaria

Kim Z, Choi BS, Kim JK, Won DI

BACKGROUND: The indirect basophil activation test using flow cytometry is a promising tool for autoimmune urticaria diagnosis. We aimed to identify better donor basophils (from atopic vs. non-atopic donors and...
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Activation of the Intrinsic Coagulation Pathway in Patients With Chronic Urticaria

Kim JA, Kim S, Kim JE, Gu JY, Yoo HJ, Kang HR, Kim HK

PURPOSE: Although coagulation activation has been reported in chronic urticaria, data pertaining to detailed changes in coagulation factors and global coagulation status are lacking. The current study evaluated global coagulation...
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Vitamin D as a Marker for Disease Severity in Chronic Urticaria and Its Possible Role in Pathogenesis

Woo YR, Jung KE, Koo DW, Lee JS

BACKGROUND: Chronic urticaria is defined as repeated episodes of wheals lasting for 6 weeks or longer. Nowadays, the role of vitamin D in various chronic diseases is a matter of...
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Comparison of MAST-CLA System Results and Allergen Detection Rates between Acute and Chronic Urticaria Patients in Gangwon, Yeongseo Province, Korea

Chung HC, Ahn SK

  • KMID: 2246085
  • Korean J Dermatol.
  • 2015 Jun;53(5):374-380.
BACKGROUND: The multiple allergosorbent test chemiluminescent assay (MAST-CLA) is a simple system with high sensitivity and specificity for measuring total and allergen-specific IgE antibodies in patients with allergic skin diseases...
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Association Between PTPN22 Polymorphisms and IgE Responses to Staphylococcal Superantigens in Chronic Urticaria

Palikhe S, Kim SH, Pham LD, Ye YM, Park HS

Protein tyrosine phosphatase-22 (PTPN22) gene encodes lymphoid-specific tyrosine phosphatase (Lyp), an inhibitor of T cell activation. A polymorphism of the PTPN22 gene has been found to be associated with chronic...
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Approaches to the diagnosis and management of chronic urticaria in children

Choi SH, Baek HS

Most guidelines for chronic urticaria (CU) in infants and children are based on limited pediatric evidence. Current evidence used to guide treatment in children is extrapolated from data focusing on...
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Vitamin D Status and Its Relationship with Disease Severity/activity in Patients with Atopic Dermatitis, Psoriasis, and Chronic Idiopathic Urticaria in Korea

Kim W, Kim JY, Park MY, Song M, Kim HS, Ko HC, Kim BS, Kim MB

  • KMID: 1789607
  • Korean J Dermatol.
  • 2015 Mar;53(3):209-216.
BACKGROUND: Deficiency of vitamin D is reported to be an important factor associated with various dermatoses such as atopic dermatitis, psoriasis, urticaria, and skin cancers. However, this association is disputable...
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