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Distribution of phospholipase C isozymes in normal human lung tissue and their immunohistochemical localization

Hwang SC, Park KH, Ha MJ, Noh IS, Park TB, Lee YH

Phospholipase C(PLC) plays a central role in signal transduction and it is important in cellular growth, differentiation and transformation. There are currently ten known mammalian isozymes of PLC identified and...
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Production of Soluble VEGF Receptor Mutants for Inhibition of Angiogenesis

Yun SY, Hong YK, Lee Y, Kim K, Kim HK, Joe YA

  • KMID: 2175025
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):595-604.
PURPOSE: Vascular endothelial growth factor (VEGF) is a potent angiogenic factor of many solid tumors, promoting vascularization and formation of metastases. In an attempt to generate effective VEGF inhibitors, the authors constructed...
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