- Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. I. Purification and some properties of AP DNA endonucleases in rat liver chromatin
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Kim YS, Kim JW, Lee SE, Oh SH
- KMID: 1421490
- J Korean Med Sci.
- 1990 Sep;5(3):127-135.
- doi: 10.3346/jkms.1990.5.3.127
Three kinds of apurinic/apyrimidinic (AP) DNA endonuclease, APcI, APcII, APcIII, were purified from rat liver chromatin through 1M KCl extraction, DEAE-trisacryl ion exchange chromatography. Sephadex G-150 gel filtration and AP... -
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- Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. II. Kinetic properties of AP DNA endonucleases in rat liver chromatin
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Kim YS, Kim JW, Lee SE, Oh SH
- KMID: 1421491
- J Korean Med Sci.
- 1990 Sep;5(3):137-143.
- doi: 10.3346/jkms.1990.5.3.137
An experiment was designed to investigate the reaction mechanism of AP (apurinic or apyrimidinic) DNA endonucleases (APcI, APcII, APcIII) purified from rat liver chromatin. Sulfhydryl compounds (2-mercaptoethanol, dithiothreitol) brought about... -
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