- Ectopic expression of cyclooxygenase-2-induced dedifferentiation in articular chondrocytes
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Lee WK, Yu SM, Cheong SW, Sonn JK, Kim SJ
- KMID: 1072952
- Exp Mol Med.
- 2008 Dec;40(6):721-727.
- doi: 10.3858/emm.2008.40.6.721
Cyclooxygenase-2 (COX-2) is known to modulate bone metabolism, including bone formation and resorption. Because cartilage serves as a template for endochondral bone formation and because cartilage development is initiated by... -
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- 2-Deoxy-D-glucose regulates dedifferentiation through beta-catenin pathway in rabbit articular chondrocytes
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Yu SM, Kim HA, Kim SJ
- KMID: 1104210
- Exp Mol Med.
- 2010 Jul;42(7):503-513.
- doi: 10.3858/emm.2010.42.7.051
2-deoxy-D-glucose (2DG) is known as a synthetic inhibitor of glucose. 2DG regulates various cellular responses including proliferation, apoptosis and differentiation by regulation of glucose metabolism in cancer cells. However, the... -
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- Growth impairment of primary chondrocyte cells by serum of rats with chronic renal failure
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Mak RH, Chang SL, Pak YK
- KMID: 1097106
- Exp Mol Med.
- 2004 Jun;36(3):243-250.
Insulin-like growth factor (IGF)/IGF binding protein (IGFBP) abnormalities may be important in the pathogenesis of growth failure in chronic renal failure (CRF). We induced experimental CRF by 5/6 nephrectomy in... -
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- Chondrogenic Differentiation of Mesenchymal Stem Cells and Its Clinical Applications
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Lee JW, Kim YH, Kim SH, Han SH, Hahn SB
- KMID: 1726144
- Yonsei Med J.
- 2004 Jun;45(Suppl):S41-S47.
- doi: 10.3349/ymj.2004.45.Suppl.41
Tissue engineering has the potential to provide cartilaginous constructs capable of restoring the normal function of native articular cartilage following joint injury or degradation. One approach to functional tissue engineering... -
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- Transplantation of a Scaffold-Free Cartilage Tissue Analogue for the Treatment of Physeal Cartilage Injury of the Proximal Tibia in Rabbits
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Lee SU, Lee JY, Joo SY, Lee YS, Jeong C
- KMID: 2374051
- Yonsei Med J.
- 2016 Mar;57(2):441-448.
- doi: 10.3349/ymj.2016.57.2.441
PURPOSE: The purpose of this study was to investigate the effects of transplantation of an in vitro-generated, scaffold-free, tissue-engineered cartilage tissue analogue (CTA) using a suspension chondrocyte culture in a... -
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