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The Relationship between Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Measured by Controlled Attenuation Parameter

Chon YE, Kim KJ, Jung KS, Kim SU, Park JY, Kim DY, Ahn SH, Chon CY, Chung JB, Park KH, Bae JC, Han KH

PURPOSE: The severity of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes mellitus (T2DM) population compared with that in normal glucose tolerance (NGT) individuals has not yet been quantitatively...
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Prognostic Indicators for Acute Liver Failure Development and Mortality in Patients with Hepatitis A: Consecutive Case Analysis

Shin HS, Kim SP, Han SH, Kim DY, Ahn SH, Han KH, Chon CY, Park JY

PURPOSE: Due to the seroepidemiological shift in hepatitis A (HA), its severity, mortality, and complications have increased in recent years. Thus, the aim of this study was to identify predictive...
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Quasispecies and Pre-Existing Drug-Resistant Mutations of Hepatitis B Virus in Patients with Chronic Hepatitis B

Kim DY, Chang HY, Lim SM, Kim SU, Park JY, Kim JK, Lee KS, Han KH, Chon CY, Ahn SH

BACKGROUND/AIMS: To investigate pre-existing hepatitis B virus (HBV) quasispecies and the genotypic evolution of several variants. METHODS: From six patients with lamivudine (LAM) failure, serum samples at pretreatment, 6 months of...
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Antiviral efficacies of currently available rescue therapies for multidrug-resistant chronic hepatitis B

Park MS, Kim BK, Kim KS, Kim JK, Kim SU, Park JY, Kim DY, Baartarkhuu O, Han KH, Chon CY, Ahn SH

BACKGROUND/AIMS: The incidence of multidrug-resistant (MDR) chronic hepatitis B (CHB) during sequential lamivudine (LAM) and adefovir dipivoxil (ADV) treatment is increasing. We investigated the antiviral efficacies of various rescue regimens...
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Predictors of Refractory Ascites Development in Patients with Hepatitis B Virus-Related Cirrhosis Hospitalized to Control Ascitic Decompensation

Seo JH, Kim SU, Park JY, Kim DY, Han KH, Chon CY, Ahn SH

PURPOSE: Refractory ascites (RA) is closely related to a high morbidity and mortality. In this study, we investigated predictors of RA development in patients with hepatitis B virus (HBV)-related cirrhosis...
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How Many Valid Measurements Are Necessary to Assess Liver Fibrosis Using FibroScan(R) in Patients with Chronic Viral Hepatitis? An Analysis of Subjects with at Least 10 Valid Measurements

Jang HW, Kim SU, Park JY, Ahn SH, Han KH, Chon CY, Park YN, Choi EH, Kim DY

PURPOSE: Using FibroScan(R) to obtain a reliable liver stiffness measurement (LSM) may require more than 10 valid measurements (VMs), according to the manufacturer's recommendations. However, this requirement lacks scientific evidence...
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Spontaneous Bacterial Peritonitis in Patients with Hepatitis B Virus-Related Liver Cirrhosis: Community-Acquired versus Nosocomial

Kim SU, Chon YE, Lee CK, Park JY, Kim DY, Han KH, Chon CY, Kim S, Jung KS, Ahn SH

PURPOSE: Spontaneous bacterial peritonitis (SBP) frequently develops in patients with liver cirrhosis; however, there is little data to suggest whether the acquisition site of infection influences the prognosis. This study...
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Acute Variceal Hemorrhage in Patients with Liver Cirrhosis: Weekend versus Weekday Admissions

Byun SJ, Kim SU, Park JY, Kim BK, Kim DY, Han KH, Chon CY, Ahn SH

PURPOSE: Little is known about the impact of weekend admission on acute variceal hemorrhage (AVH). Thus, we investigated whether day of admission due to AVH influenced in-hospital mortality. MATERIALS AND METHODS:...
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Clinicopathological Characteristics in Combined Hepatocellular-Cholangiocarcinoma: A Single Center Study in Korea

Park H, Choi KH, Choi SB, Choi JW, Kim DY, Ahn SH, Kim KS, Choi JS, Han KH, Chon CY, Park JY

PURPOSE: Combined hepatocellular-cholangiocarcinoma (CHCC) is an uncommon form of cancer, and its clinicopathological features have rarely been reported in detail. This study was undertaken to evaluate the clinicopathological characteristics and...
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A Case of Hepaticoduodenal Fistula Development after Transarterial Chemoembolization in Patient with Hepatocellular Carcinoma

Park YH, Kang SH, Kim SU, Kim DY, Park JY, Ahn SH, Han KH, Chon CY

Transarterial chemoembolization (TACE) is recommended as one of the first line therapy for unresectable hepatocellular carcinoma (HCC). Rupture of HCC following TACE is a rare and potentially fatal complication. We...
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A Case of Embryonal Sarcoma of the Liver Mimicking a Hydatid Cyst in an Adult

Yoon JY, Lee JM, Kim DY, Choi GH, Park YN, Chung JW, Kim EY, Park JY, Ahn SH, Han KH, Chon CY

  • KMID: 2284193
  • Gut Liver.
  • 2010 Jun;4(2):245-249.
An undifferentiated (embryonal) liver sarcoma (ULS) originates from a primitive mesenchymal cell, with a predilection for childhood and very rare occurrence in adults. We report a case of a ULS...
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Clinical Efficacy of a 24-months Course of Lamivudine Therapy in Patients with HBeAg Negative Chronic Hepatitis B: A Long-term Prospective Study

Paik YH, Kim JK, Kim DY, Park JY, Ahn SH, Han KH, Chon CY, Lee KS

The optimal duration of oral nucleos(t)ide analogue therapy for HBeAg negative chronic hepatitis B (CHB) has not been defined. The aim of this study was to investigate the clinical efficacy...
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Deficiencies in proteins C and S in a patient with idiopathic portal hypertension accompanied by portal vein thrombosis

Hwang S, Kim DY, Kim M, Chon YE, Lee HJ, Park YN, Park JY, Ahn SH, Han KH, Chon CY

Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal portal hypertension. Among various hepatoportal disorders, noncirrhotic portal hypertension conditions such as idiopathic portal hypertension (IPH) are considered to have...
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Hepatogastric fistula caused by direct invasion of hepatocellular carcinoma after transarterial chemoembolization and radiotherapy

Park H, Kim SU, Choi J, Park JY, Ahn SH, Han KH, Chon CY, Park YN, Kim DY

A 63-year-old man with a history of hepatitis-B-related hepatocellular carcinoma (HCC) in the left lateral portion of the liver received repeated transcatheter arterial chemoembolization (TACE) and salvage radiotherapy. Two months...
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A Case of Hepatic Congestion Due to Right Heart Failure Mimicking Liver Tumor

Shin DH, Lee MH, Kim DY, Lee KJ, Park JY, Ahn SH, Han KH, Chon CY

This report describes a patient with hepatic congestion due to right heart failure mimicking liver tumor. The patient had a history of breast cancer and left total mastectomy 30 years...
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Two cases of sarcomatoid carcinoma of the liver associated with glomerulonephritis

Park HN, Choi JW, Park JY, Park YN, Kim DY, Han KH, Chon CY

  • KMID: 2258093
  • Korean J Med.
  • 2009 Aug;77(Suppl 1):S1-S6.
Sarcomatoid carcinoma is a rare malignant neoplasm that may develop in various organs. Hepatocellular carcinoma with sarcomatous changes after anticancer therapy, such as hepatic arterial chemoembolization, has been reported, but...
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Usefulness and Safety of Extracorporeal Liver Support Therapy Using MARS(R) for Patients with Liver Failure: A Preliminary Report

Choi JW, Yoon KT, Park JY, Kim JK, Ahn SH, Paik YH, Lee KS, Han KH, Chon CY, Kim DY

BACKGROUND/AIMS: The molecular adsorbent recirculating system (MARS(R)) is a form of artificial extracorporeal liver support and can be used for a bridge to spontaneous recovery of hepatic function or liver...
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Recombinant Interferon-Beta-1alpha Plus Ribavirin for the Treatment of Chronic HCV Infection: A Prospective, Randomized, Comparative Pilot Study

Ahn SH, Lee HW, Kim YS, Kim JK, Han KH, Chon CY, Moon YM

  • KMID: 1744235
  • Gut Liver.
  • 2009 Mar;3(1):20-25.
BACKGROUND/AIMS: Interferon beta (IFN-beta) has been shown to have antiviral activity, and thus could be useful in treating viral infections. Therefore, we compared the efficacy and safety of recombinant IFN-beta(IFN-beta-1a)...
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A comparison of 24- vs. 48-week peginterferon plus ribavirin in patients with genotype 1 chronic hepatitis C

Kim MN, Yoon KT, Park JY, Kim DY, Ahn SH, Chon CY, Han KH

BACKGROUND/AIMS: The standard therapy for patients with genotype 1 chronic hepatitis C (CHC) is a combination of peginterferon and ribavirin for 48 weeks. However, the most appropriate duration of treatment...
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Clinical outcomes of systemic chemotherapy in hepatocellular carcinoma patients with multiple lung metastases

Yoon KT, Choi JW, Park JY, Ahn SH, Paik YH, Lee KS, Han KH, Chon CY, Kim DY

BACKGROUND/AIMS: Advanced hepatocellular carcinoma (HCC) with multiple lung metastases has a poor prognosis with no effective treatment having been established. This study evaluated the outcomes of systemic chemotherapy for...
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