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Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes

An S, Jang YS, Park JS, Kwon BM, Paik YK, Jeong TS

We investigated the mechanism of spontaneous cholesterol efflux induced by acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibition, and how an alteration of cholesterol metabolism in macrophages impacts on that in HepG2 cells....
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Topology of Scavenger Receptor Class B Type I (SR-BI) on Brush Border Membrane

Han CH, Lee MH

  • KMID: 1097342
  • J Vet Sci.
  • 2002 Dec;3(4):265-272.
Both hydropathy plot and in vitro translation results predict the topology of SR-BI; the receptor is an integral membrane protein of 509 amino acids, consisting of a short cytoplasmic N-terminus...
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