- Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death
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Seok JH, Park KA, Byun HS, Won M, Shin S, Choi BL, Lee H, Kim YR, Hong JH, Park J, Hur GM
- KMID: 1838357
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):185-191.
- doi: 10.4196/kjpp.2008.12.4.185
Activation of c-Jun N-terminal kinase (JNK), a member of the mitogen-activated protein kinase family, is an important cellular response that modulates the outcome of the cells which are exposed to... -
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- Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase
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Byun HS, Won M, Park KA, Kim YR, Choi BL, Lee H, Hong JH, Piao L, Park J, Kim JM, Kweon GR, Kang SH, Han J, Hur GM
- KMID: 1052941
- Exp Mol Med.
- 2008 Apr;40(2):186-195.
- doi: 10.3858/emm.2008.40.2.186
Previous studies have demonstrated that rottlerin, a specific PKCdelta inhibitor, potentiates death receptor- mediated apoptosis through a cytochrome c-dependent or -independent pathway. However, its ability to regulate necrotic cell death,... -
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