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Programmed cell death-ligand 1 assessment in urothelial carcinoma: prospect and limitation

Lee KS, Choe G

Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibition has revolutionized the treatment paradigm of urothelial carcinoma (UC). Several PD-L1 assays are conducted to formulate appropriate treatment decisions for PD-1/PD-L1...
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Case Series of Antrovestibular Polyp: An Unusual Growth of Antral Polyp Toward the Nasal Vestibule Through the Anterior Fontanelle

Choe G, Gelera JE, Kim JW

Background and Objectives: This case series is aimed to introduce a new term, antrovestibular polyp (AVP), for an antral polyp herniating anteriorly toward the nasal vestibule and to describe an...
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Concurrent and Adjuvant Temozolomide for Newly Diagnosed Grade IIIGliomas without 1p/19q Co-deletion: A Randomized, Open-Label,Phase 2 Study (KNOG-1101 Study)

Hwang K, Kim TM, Park CK, Chang JH, Jung TY, Kim JH, Nam DH, Kim SH, Yoo H, Hong YK, Kim EY, Lee DE, Joo J, Kim YJ, Choe G, Choi BS, Kang SG, Kim JH, Kim CY

Purpose We investigated the efficacy of temozolomide during and after radiotherapy in Korean adults with anaplastic gliomas without 1p/19q co-deletion. Materials and Methods This was a randomized, open-label, phase 2 study and notably the...
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Case Report of Urinary Schistosomiasis in a Returned Traveler in Korea

Lee Y, Song HB, Jung BK, Choe G, Choi MH

A 23-year-old Korean woman with a residence history in Kenya and Malawi for about 2 years presented with gross hematuria for 1 month. Blood tests were within normal range except...
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Clinical Characteristics of High-Grade Glioma with Primary Leptomeningeal Seeding at Initial Diagnosis in a Single Center Study

Kwon JE, Hwang K, Go KO, Wee CW, Kim IA, Kim YJ, Choe G, Choi BS, Han JH, Kim CY

Background High-grade glioma (HGG) with primary leptomeningeal seeding (PLS) at initial diagnosis is rare. The purpose of this study was to identify its clinical features and to describe the clinical...
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Reclassification of Mongolian Diffuse Gliomas According to the Revised 2016 World Health Organization Central Nervous System Tumor Classification

Ochirjav E, Enkhbat B, Baldandorj T, Choe G

BACKGROUND: The 2016 World Health Organization (WHO) classification of central nervous system (CNS) tumors has been modified to incorporate the IDH mutation and 1p/19q co-deletion in the diagnosis of diffuse...
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Revisiting the Clinical Scoring System for the Prognosis of Chronic Rhinosinusitis with Nasal Polyps

Kim JY, Han YE, Seo Y, Choe G, Kim MK, Huh G, Cho D, Yang SK, Kang SH, Kim DW

PURPOSE: To evaluate the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) classification, a clinical scoring system, for predicting disease control status in chronic rhinosinusitis with nasal polyps (CRSwNP)...
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Analysis of Sleep Questionnaires of Commercial Vehicle Operators in Korea

Song Y, Park HG, Song S, Lee DH, Huh G, Hyun SJ, Choe G, Han SA, Ji JY, Kim JK, Kim HJ

BACKGROUND AND OBJECTIVES: Obstructive sleep apnea (OSA) is highly prevalent in commercial vehicle operators (CMVOs). This study aimed to evaluate the poor sleep quality, daytime sleepiness, and the prevalence of...
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Prediction of Obstructive Sleep Apnea Based on Respiratory Sounds Recorded Between Sleep Onset and Sleep Offset

Kim JW, Kim T, Shin J, Choe G, Lim HJ, Rhee CS, Lee K, Cho SW

OBJECTIVES: To develop a simple algorithm for prescreening of obstructive sleep apnea (OSA) on the basis of respiratorysounds recorded during polysomnography during all sleep stages between sleep onset and offset. METHODS:...
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Fourth Ventricle Neurenteric Cyst Mimicking Hemangioblastoma

Choe E, Hwang K, Choe G, Kim CY

This report presents a case of fourth ventricle neurenteric cyst (NE cyst) mimicking hemangioblastoma, which developed in a 50-year-old woman. A tiny enhancing mural portion of the fourth ventricle in...
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Focal lesion at the midline of the prostate on transrectal ultrasonography: take it or leave it?

Kim J, Hwang SI, Lee HJ, Hong SK, Byun SS, Lee S, Choe G

PURPOSE: The purpose of this study was to analyze the detection rate of prostate cancers from targeted biopsy specimens of midline focal lesions and to investigate the ultrasonographic findings to...
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Stromal Expression of MicroRNA-21 in Advanced Colorectal Cancer Patients with Distant Metastases

Lee KS, Nam SK, Koh J, Kim DW, Kang SB, Choe G, Kim WH, Lee HS

BACKGROUND: The aim of this study was to determine the regional heterogeneity and clinicopathological significance of microRNA-21 (miR-21) in advanced colorectal cancer (CRC) patients with distant metastasis. METHODS: miR-21 expression was...
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Hypothalamic Extraventricular Neurocytoma (EVN) in a Pediatric Patient: A Case of EVN Treated with Subtotal Removal Followed by Adjuvant Radiotherapy

Cho M, Joo JD, Kim BH, Choe G, Kim CY

Extra ventricular neurocytoma (EVN) is a rare brain tumor with histologic features similar with a central neurocytoma, but located outside of the ventricular system. In this study, we present an...
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The role of pathologists in multidisciplinary cancer care

Lee KS, Choe G

In recent years there has been significant growth in multidisciplinary cancer treatment. In cancer patient management, multidisciplinary cancer treatment is essential for evaluation of treatment response and proper decision making....
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Expression of c-MET in Invasive Meningioma

Yun S, Koh JM, Lee KS, Seo AN, Nam KH, Choe G

BACKGROUND: Meningiomas show high recurrence rates even after curative tumor removal. The invasiveness of meningiomas may contribute to their high recurrence rates. Recently, c-MET and hepatocyte growth factor (HGF) have...
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Synovial Osteochondromatosis of the Cervical Spine: A Case Report

Chee CG, Lee JW, Lee GY, Yeom JS, Choe G, Kang HS

Synovial osteochondromatosis is a rare, benign condition characterized by formation of cartilaginous nodules within the synovium. It rarely occurs at cervical spine, and only six cases have been previously reported...
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Silent Giant Cell Arteritis in an Elderly Korean Woman

Cha DM, Lee T, Choe G, Yang HK, Hwang JM

Giant cell arteritis (GCA) is a rare disease among Asians. Arteritic anterior ischemic optic neuropathy, which accompanies GCA, has not yet been reported in Koreans. Diagnosis of GCA is difficult...
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Immunohistochemical Classification of Primary and Secondary Glioblastomas

Lee KS, Choe G, Nam KH, Seo AN, Yun S, Kim KJ, Cho HJ, Park SH

  • KMID: 2012155
  • Korean J Pathol.
  • 2013 Dec;47(6):541-548.
BACKGROUND: Glioblastomas may develop de novo (primary glioblastomas, P-GBLs) or through progression from lower-grade astrocytomas (secondary glioblastomas, S-GBLs). The aim of this study was to compare the immunohistochemical classification of...
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Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia

Lim JH, Kim N, Lee HS, Choe G, Jo SY, Chon I, Choi C, Yoon H, Shin CM, Park YS, Lee DH, Jung HC

  • KMID: 2053514
  • Gut Liver.
  • 2013 Jan;7(1):41-50.
BACKGROUND/AIMS: Intestinal metaplasia (IM) is a premalignant condition. This study aimed to evaluate the correlation between endoscopic and histological findings of IM. METHODS: The cases of IM were graded by conventional...
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Liquid-Based Cytology of Villoglandular Adenocarcinoma of the Cervix: A Report of 3 Cases

Choi Y, Kim H, Choi H, Hwang D, Choe G, Chung JH, Park SY, Lee HS, Paik JH, Park HJ

  • KMID: 2011993
  • Korean J Pathol.
  • 2012 Apr;46(2):215-220.
Villoglandular adenocarcinoma (VGA) is a rare subtype of cervical adenocarcinoma with a more favorable prognosis compared to conventional adenocarcinomas. Although the tumors are usually recognized on colposcopic examination due to...
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