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Anti-cancer effect of glabridin by reduction of extracellular vesicles secretion in MDA-MB-231 human breast cancer cells

Choi SH, Hwang JH, Baek MC, Cho YE

Purpose: Glabridin (GD) is a bio-available isoflavane isolated from the root extract of licorice (Glycyrrhiza glabra L.). It exhibits a variety of pharmacological activities such as antiinflammatory and anti-oxidant activities....
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Computer-guided implant surgery and immediate provisionalization by chair-side CAD-CAM: A case report

Hyun SW, Leesungbok R, Lee SW, Cho YE

This report demonstrates a method of generating a chair-side and computer-aided template for implant surgery based on the Top-Down and restoration-driven concept. Compared to the traditional CAD-CAM process which requires...
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Influence of Frailty on Life Expectancy in Octogenarians After Lumbar Spine Surgery

Jang HJ, Chin DK, Park JY, Kuh SU, Kim KS, Cho YE, Kim KH

Objective: Many studies have reported positive surgical outcomes and decreased mortality after spine surgery in the elderly population, including patients between 85 and 90 years of age. Here, in addition...
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The Fate of Proximal Junctional Vertebral Fractures after Long-Segment Spinal Fixation : Are There Predictable Radiologic Characteristics for Revision surgery?

Jang HJ, Park JY, Kuh SU, Chin DK, Kim KS, Cho YE, Hahn BS, Kim KH

Objective : To investigate the radiographic characteristics of the uppermost instrumented vertebrae (UIV) and UIV+1 compression fractures that are predictive of revision surgery following long-segment spinal fixation. Methods : A total...
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Revision Surgery for a Failed Artificial Disc

Kim KR, Chin DK, Kim KS, Cho YE, Shin DA, Kim KN, Kuh SU

Purpose: This study aimed to present our experience with failures in C-TDR and revision surgery outcomes. Materials and Methods: We retrospectively examined patients who underwent revision surgery due to the failure...
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Surgical Strategy for Sacral Tumor Resection

Kim KR, Kim KH, Park JY, Shin DA, Ha Y, Kim KN, Chin DK, Kim KS, Cho YE, Kuh SU

Purpose: This study aimed to present our experiences with a precise surgical strategy for sacrectomy. Materials and Methods: This study comprised a retrospective review of 16 patients (6 males and 10...
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The function of zinc in the primary vascular smooth muscle cell proliferation in rats

Cho YE, Kwun IS

Purpose: The vascular smooth muscle cells (VSMCs) in mature animals have implicated to play a major role in the progression of cardiovascular diseases such as atherosclerosis. This study aimed at...
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Application of 3D printing technology for rehabilitating maxillary defects

Cho YE, Ohkubo C, Park EJ

The use of an obturator prosthesis for patients with maxillary defects is a common treatment method to improve their oral function and achieve esthetic satisfaction. However, due to various difficulties...
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Zinc modulation of osterix in MC3T3-E1 cells

Seo HJ, Jeong JB, Cho YE, Kwun IS

Purpose: Zinc is known to be associated with osteoblast proliferation and differentiation. Osterix as zinc-finger transcription factor is also related to osteoblast differentiation and bone formation. In the present study, we...
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Exosomal Protein Profiles as Novel Biomarkers in Weight Gain After Kidney Transplantation: A Pilot Study

Cho YE, Lee H, Kim H, Yun S, Ann C

Purpose: Weight gain after kidney transplantation is a critical factor that can lead to poor outcomes with cardiovascular complications. Many studies have been conducted to identify predictive markers of future...
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Effect of mixing method and storage time on dimensional stability of alginate impressions materials

Bang HJ, Shim HA, Cho YE, Park EJ

Purpose: The purpose of this study is to compare the volume stability depending on the mixing methods and storage time for the conventional alginate and extended-pour alginate. Materials and methods: An...
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Effect of corosolic acid on apoptosis and angiogenesis in MDA-MB-231 human breast cancer cells

Son KH, Hwang Jh, Kim Dh, Cho YE

Purpose: Corosolic acid (CA), also known as 2α-hydroxyursolic acid, is present in numerous plants, and is reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells such as osteosarcoma,...
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The Future of Spine Surgery in the Fourth Industrial Revolution: Telerobotic Spine Surgery

Cho YE

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Full mouth rehabilitation in a patient with peri-implantitis: A case report

Choi NH, Cho YE, Park EJ

Peri-implantitis appears in almost 20% of patients who received implant treatment, and increase in its number is inevitable as time goes by. Although it can be treated by both non-surgical...
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Epidemiology of C5 Palsy after Cervical Spine Surgery: a 21-Center Study

Oh JK, Hong JT, Kang DH, Kim SW, Kim SW, Kim YJ, Chung CK, Shin JJ, Yi S, Lee JK, Lee JH, Lee CH, Lee HJ, Chun HJ, Cho DC, Cho YE, Jin YJ, Choi KC, Han IH, Hyun SJ, Hur JW, Kim KJ

OBJECTIVE: C5 palsy is a severe complication after cervical spine surgery, the pathophysiology of which remains unclear. This multicenter study investigated the incidence of C5 palsy following cervical spine surgery...
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Cellular zinc deficiency inhibits the mineralized nodule formation and downregulates bone-specific gene expression in osteoblastic MC3T3-E1 cells

Cho YE, Kwun IS

PURPOSE: Zinc (Zn) is an essential trace element for bone mineralization and osteoblast function. We examined the effects of Zn deficiency on osteoblast differentiation and mineralization in MC3T3-E1 cells. METHODS: Osteoblastic...
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Performance of MALDI Biotyper for Species Identification of Carbapenem-Resistant Enterobacteriaceae by Media Types and Incubation Time

Cho YE, Choi BH, Chang J, Sung H, Kim MN

BACKGROUND: This study was conducted to evaluate the impact of the media type used for direct identification of colonies on the surveillance culture of carbapenem-resistant Enterobacteriaceae (CRE) by matrix assisted...
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Glycyrrhiza uralensis (licorice) extracts increase cell proliferation and bone marker enzyme alkaline phosphatase activity in osteoblastic MC3T3-E1 cells

Cho YE, Kwun IS

PURPOSE: The Glycyrrhiza uralensis species (Leguminosae) as a medicinal biocompound, and one of its root components, isoliquritigenin (ISL), which is a flavonoid, has been reported to have anti-tumor activity in...
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Analysis of Factors Contributing to Repeat Surgery in Multi-Segments Cervical Ossification of Posterior Longitudinal Ligament

Jeon I, Cho YE

OBJECTIVE: Cervical ossification of the posterior longitudinal ligament (OPLL) can be treated via anterior or posterior approach, or both. The optimal approach depends on the characteristics of OPLL and cervical...
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Zinc upregulates bone-specific transcription factor Runx2 expression via BMP-2 signaling and Smad-1 phosphorylation in osteoblasts

Cho YE, Kwun IS

PURPOSE: Runx2 (runt-related transcription factor 2), a bone-specific transcription factor, is a key regulator of osteoblast differentiation and its expression is induced by the activation of BMP-2 signaling. This study...
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