- TProtective effect of chlormethiazole, a sedative, against acetaminophen-induced liver injury in mice
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Lee HC, Jung SA, Jung HK, Yi SY, Kim DY, Moon IH, Park SS
- KMID: 760331
- Korean J Intern Med.
- 1999 Jul;14(2):27-33.
OBJECTIVES: The hepatotoxicity of acetaminophen is not a result of the parent compound but is mediated by its reactive metabolite N-acetyl-p-benzoquinone imine. Cytochrome P4502E1 (CYP2E1) is the principal... -
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