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Interferon-gamma upregulates the stromelysin-1 gene expression by human skin fibroblasts in culture

Lee KS, Ryoo YW, Song JY

  • KMID: 754989
  • Exp Mol Med.
  • 1998 Jun;30(2):59-64.
The equilibrium between deposition and degradation of extracellular matrix(ECM) is essential to normal tissue development and repair of wound or inflammatory responses. It has recently become apparent that several cytokines and growth factors...
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Genomic structure of the regulatory region of the voltage-gated calcium channel alpha 1D

Kim HL, Chang YJ, Lee SM, Hong YS

  • KMID: 755016
  • Exp Mol Med.
  • 1998 Dec;30(4):246-251.
In excitable and endocrine organs, calcium influxes through the L-type voltage-gated calcium channel (VGCC) which is composed of four (alpha 1, alpha 2, beta, and gamma) subunits. Temporal and spatial...
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Characterization of regulatory elements on the promoter region of human ATP-citrate lyase

Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW

  • KMID: 1029940
  • Exp Mol Med.
  • 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL...
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American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines

Duda RB, Kang SS, Archer SY, Meng S, Hodin RA

American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle...
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